Education, Science, Technology, Innovation and Life
Open Access
Sign In

Electrospinning Structural Parameter Design in Achilles Tendon Heals

Download as PDF

DOI: 10.23977/medsc.2023.040718 | Downloads: 7 | Views: 307


Yixuan Li 1


1 Beijing 101 Middle School, Beijing, 100000, China

Corresponding Author

Yixuan Li


Traditional achilles tendon heals methods often use traditional biomaterials, but these materials have certain limitations. According to the different conditions of achilles tendon heals injury and physical condition of each patient, traditional methods can not provide a satisfactory solution. Traditional healing methods cannot effectively simulate the biomechanical properties of the natural achilles tendon heals. This paper uses electrospinning technology to solve these problems. The fiber diameter is designed and controlled to meet the patient's achilles tendon heals requirements. By adjusting electrospinning process parameters, nozzle diameter and voltage, fibers with excellent performance can be obtained. The structure parameters of electrospinning were used to design and adjust the fiber arrangement to simulate the structure of natural achilles tendon heals. Optimizing the connection between the different fiber layers in electrospinning can improve the biocompatibility of the film. On this basis, this paper combined with electrospinning structural parameter design, designed a personalized three-dimensional model. The findings highlight the importance of electrospinning technology in the design of personalized achilles tendon heals devices, which enables fine control of fiber diameter to meet individual patient needs. After testing, the connection strength reached 985 n after applying a force of 1000 N, and after 10,000 load cycles, the model fraction was calculated to be 88. The research in this paper is helpful to improve the biocompatibility and durability of the healing device, and provides a solid foundation for clinical application. These results demonstrate the great potential of electrospinning technology in the design of personalized achilles tendon heals devices and provide a valuable reference for future research.


Electrospinning Technology, Achilles Tendon Heals, Structured Parameter Design, Biocompatibility Assessment


Yixuan Li, Electrospinning Structural Parameter Design in Achilles Tendon Heals. MEDS Clinical Medicine (2023) Vol. 4: 108-117. DOI:


[1] Davis R, Singh A, Jackson M J, Coelho R T, Prakash D, Charalambous C P, et al. A comprehensive review on metallic implant biomaterials and their subtractive manufacturing. The International Journal of Advanced Manufacturing Technology, 2022, 120(3-4): 1473-1530. DOI:
[2] Marin E, Boschetto F, Pezzotti G J J O B M R P A. Biomaterials and biocompatibility: An historical overview, 2020, 108(8):1617-1633. DOI:
[3] Gao F, Hu Y, Li G, Liu S, Li Q, Yang Z, et al. Layer-by-layer deposition of bioactive layers on magnesium alloy stent materials to improve corrosion resistance and biocompatibility. Bioactive materials, 2020, 5(3): 611-623. DOI:
[4] Poh P S P, Lingner T, Kalkhof S, et al. Enabling technologies towards personalization of scaffolds for large bone defect regeneration. Current Opinion in Biotechnology, 2022, 74: 263-270. DOI: 1016/j. copbio. 2021.12.002
[5] Madl C M, Heilshorn S C, Blau H M. Bioengineering strategies to accelerate stem cell therapeutics. Nature, 2018, 557(7705): 335-342. DOI:
[6] Dash B C, Xu Z, Lin L, Koo A, Ndon S, Berthiaume F, Hsia H, et al. Stem cells and engineered scaffolds for regenerative wound healing. Bioengineering, 2018, 5(1): 23. DOI:
[7] Feng Y, Zhu S, Mei D, Li J, Zhang J , Yang S, et al. Application of 3D printing technology in bone tissue engineering: a review. Current Drug Delivery, 2021, 18(7): 847-861.
[8] Liu T, Chen Y, Apicella A, Mu Z,Yu T,Huang Y, et al. Effect of porous microstructures on the biomechanical characteristics of a root analogue implant: an animal study and a finite element analysis. ACS biomaterials science & engineering, 2020, 6(11): 6356-6367. DOI:
[9] Wen X, Xiong J, Lei S, Qin X. Diameter refinement of electrospun nanofibers: From mechanism, strategies to applications. Advanced Fiber Materials, 2021: 1-17. DOI:
[10] Yu J, Kan C W. Review on fabrication of structurally colored fibers by electrospinning. Fibers, 2018, 6(4): 70. DOI:
[11] Zong H, Xia X, Liang Y, Dai S, Alsaedi A, Hayat T, et al. Designing function-oriented artificial nanomaterials and membranes via electrospinning and electrospraying techniques. Materials Science and Engineering: C, 2018, 92: 1075-1091.
[12] Ghosal K, Chandra A, Roy S, Agatemor C, Thomas S, Provaznik l, et al. Electrospinning over solvent casting: tuning of mechanical properties of membranes. Scientific reports, 2018, 8(1): 5058. DOI: 1038/ s41598-018-23378-3
[13] Rezaei F S, Sharifianjazi F, Esmaeilkhanian A, Salehi E. Chitosan films and scaffolds for regenerative medicine applications: A review. Carbohydrate polymers, 2021, 273: 118631. DOI: carbpol. 2021.118631.
[14] Liu Z, Ramakrishna S, Liu X. Electrospinning and emerging healthcare and medicine possibilities. APL bioengineering, 2020, 4(3). DOI:

Downloads: 4971
Visits: 222331

Sponsors, Associates, and Links

All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.