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A Systematic Review of the Synergy of Traditional Chinese Medicine and Western Medicine in the Treatment of Heart Failure in Dilated Cardiomyopathy

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DOI: 10.23977/medsc.2023.040720 | Downloads: 3 | Views: 171


Dan Qi 1,2, Huan Liu 2, Fangyuan Wang 2, Liangyu Cui 1,2, Yuying Qi 2, Zhou Qian 2, Jing Ma 2


1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Department of Traditional Chinese Medicine, Xijing Hospital of Air Force Medical University, Xi'an, Shaanxi, 710032, China

Corresponding Author

Huan Liu


In order to analyse the TCM treatment, TCM medication, clinical efficacy and safety of TCM synergy in the treatment of dilated cardiomyopathy heart failure, we used method of data mining was used to systematically evaluate. We searched CNKI, WanFang, VIP, Sinomad, Web of Science, Pubmed and other databases, and performed meta-analysis or descriptive analysis on clinical efficacy and LFE, LVEDD, LVESD and serum NT-ProBNP from the establishment of each database to July 2021. For the literature that meets the inclusion criteria, a database was established by selecting Chinese medicine prescriptions, and frequency statistics, association rule analysis and other methods were used to analyze Chinese medicine treatment methods, commonly used Chinese medicines and drug pairs or drug groups. Resultly, a preliminary search of 858 articles resulted in the inclusion of 20 RCTs with 1745 patients. There were 9 kinds of treatment methods involved, and the most frequently used were 29.23% for qi invigoration, 24.62% for blood revitalization, and 18.60% for water conservancy. 48 flavors of commonly used Chinese medicine, the frequency of use is 90% of astragalus, 75% of danshen and 65% of ginseng. There were 30 commonly used drug pairs or drug groups, and the high-frequency drug pairs included astragalus + danshen, laurel branch + astragalus, danshen + laurel branch, etc., and the frequency of use was 43.3%, 36.7%, 36.7%, etc. The TCM synergistic treatment group was better than the Western drug control in terms of total clinical effective rate, LFE, LVEDD, LVESD and serum NT-ProBNP. In conclusion, the main treatment methods of heart failure in dilated cardiomyopathy are qi invigoration, blood revitalization and water rejuvenation, commonly used Chinese medicines are astragalus, danshen, ginseng, etc., commonly used high-frequency drugs are astragalus + danshen, guizhi + astragalus, danshen + guizhi, etc. And the synergistic treatment of traditional Chinese and Western medicine is obviously better than that of western medicine alone.


Dilated cardiomyopathy; Heart failure; Data mining; Medication rules; Meta-analysis


Dan Qi, Huan Liu, Fangyuan Wang, Liangyu Cui, Yuying Qi, Zhou Qian, Jing Ma, A Systematic Review of the Synergy of Traditional Chinese Medicine and Western Medicine in the Treatment of Heart Failure in Dilated Cardiomyopathy. MEDS Clinical Medicine (2023) Vol. 4: 128-136. DOI:


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