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Review of Researches on Non-genetic Factors of Embryo Termination

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DOI: 10.23977/medsc.2023.040816 | Downloads: 15 | Views: 336

Author(s)

Qinhan Xie 1

Affiliation(s)

1 The Second Clinical College, Guangzhou Medical University, Guangzhou, Guangdong, 511495, China

Corresponding Author

Qinhan Xie

ABSTRACT

Embryo termination is a common gynecological disease with an incidence of 10% ~15%, which occurs mainly in the 12th week of pregnancy. After embryo termination, there are generally no obvious discomfort symptoms, so early diagnosis is difficult and timely and effective treatment cannot be carried out, which seriously endangers the physical health of women and threatens their health. In order to clarify the factors and pathogenesis that cause embryo termination, many experts and researchers at home and abroad have conducted studies on embryo termination. Based on this, the relevant research on non-genetic influencing factors leading to embryo exposure will be reviewed from the perspectives of uterine microbiota, endocrine factors, immune factors and social psychology. The aim is to provide references and ideas for further exploration of mechanisms and intervention measures related to embryo exposure, thereby providing reference to research and improvement of maternal health.

KEYWORDS

Embryo termination; Factor; Non-genetic; Research progress

CITE THIS PAPER

Qinhan Xie, Review of Researches on Non-genetic Factors of Embryo Termination. MEDS Clinical Medicine (2023) Vol. 4: 105-111. DOI: http://dx.doi.org/10.23977/medsc.2023.040816.

REFERENCES

[1] Wang Haixia, Wang Yuna, LIU Haifang, et al. Construction of a prediction model for the risk of embryonic arrest and the effect of preventive care based on risk factors[J]. Journal of Xinjiang Medical University,2023,46(3):418-422. 
[2] Zhao Xiaojuan, Wei Ke, Dong Fei et al. Analysis of the incidence of embryonic termination and the factors affecting it in 8693 cases of women of childbearing age[J]. Hainan Medicine,2023,34(14):2075-2078.
[3] Shen Yaqian. Influence of vaginal microecology on the outcome of in vitro assisted conception in patients with unexplained recurrent embryo implantation failure[D]. Shandong University,2022.
[4] Wang Yao. Study on the effect of uterine microbiota on pregnancy outcome in infertile women [D]. China Medical University, 2021.
[5] Luan Zonghui, Liu Ruyue, Han Changli et al. Progress in the study of the correlation between uterine microecology and embryonic termination[J]. Journal of Practical Obstetrics and Gynaecology,2023,39(01):43-46.
[6] Luo W. Study on the correlation between embryonic termination and vaginal microbiota [D]. Lanzhou University,2021.
[7] Moreno I,Codoñer FM, Vilella F,et al.Evidence that the endometrial microbiota has an effect on implantation success or failure[J].Am JOhstet Gynecol,2016,215(6):684-703.
[8] Li W,Junyu C,Lin H, et al. Association between the vaginal and uterine microbiota and the risk of early embryonic arrest.[J]. Frontiers in microbiology,2023,14.
[9] Wang R, Qiao Yuan, Xiong Xiancui. Study on the impact of Mycoplasma hyopneumoniae infection on pregnancy outcome during pregnancy[J]. Guizhou Medicine,2022,46(12):1907-1908.
[10] Xing Lizhi. Correlation study of vaginal bacterial communities in patients with early pregnancy embryonic arrest[D]. Lanzhou University,2021.
[11] Benner M, Ferwerda G,Joosten I, et al. How uterine microbiota mightbe responsible for a receptive, fertile endometrium [J].Hum ReprodUpdate,2018 ,24(4):393-415.
[12] Li Zhihui, Sun Jiazhen,LEI Ming et al.Expression of MMP-2 in chorionic villi and meconium tissues of patients with embryonic foetal termination and its clinical significance[J]. Journal of Clinical Rational Drug Use,2016,9(09):105-106.
[13] Zeng Xiaofang. Correlation between chlamydia and mycoplasma infections and serum chorionic gonadotropin (β-HCG) and progesterone (P) levels and embryonic arrest in pregnant women[J]. Modern Diagnosis and Treatment, 2019, 30(07):1130-1132.
[14] Zhao Chan. Study on the correlation between Chinese medicine evidence and endocrine factors in embryonic foetal termination [D]. Fujian University of Traditional Chinese Medicine,2020.
[15] Gao Yang,Guan Junhua. Analysis of the correlation between progesterone level and embryonic foetal termination in early pregnancy [J]. China Primary Health Care,2021,35(5):86-88.
[16] LI Zhonghui, LIU Jiangmei, Liang Dongru. Relationship between serum chorionic gonadotropin and progesterone levels and embryonic arrest[J]. Hainan Medicine,2018,29(13):1877-1878.
[17] Duo Xiaoling. Analysis of the correlation between serum hCG, PROG and E2 levels and miscarriage and embryonic arrest in early pregnancy[J]. China Maternal and Child Health,2017,32(3):566-569.
[18] Wu Xiaorong,WANG Shuangshuang,Cao Yila. Relationship between serum Th1/Th2 cytokines and progesterone, β-HCG levels and pregnancy outcome in patients with early pregnancy preeclampsia combined with subchorionic haematoma [J]. Hainan Medicine,2023,34(09):1290-1294.
[19] Lu Xixi. Study on the relationship between serum thyroid hormone level and VEGF expression in chorionic tissue of patients with embryonic foetal termination[D]. Qingdao University,2020.
[20] Han Hua, LI Jianling, Yang Dandan. Determination of uterine artery and superior thyroid artery blood flow parameters and serum hormone levels in early pregnancy in pregnant women with embryonic foetal termination[J]. Journal of Zhengzhou University (Medical Edition),2022,57(1):102-107. 
[21] Cui S-H, Zhao L-L, Cai Y-M, et al. Role of interleukin-6 and matrix metalloproteinase-2 in early embryonic development [J]. Journal of practical medicine,2014(6):905-908. 
[22] Liu Bingbing,Xu Yanning,Chen Ling. Relationship between inflammatory cytokines and embryonic sterilisation[J]. International Journal of Obstetrics and Gynaecology,2023,50(04):409-415.
[23] Zhang Feng-Min,Hao Wei-Ming,LI Hong-Xia et al. Analysis of risk factors associated with embryonic termination in patients with assisted reproduction[J]. China Maternal and Child Health Care,2021,36(15):3534-3537.
[24] Wang Juan, Wang Chen, Yang Fengna et al. Clinical analysis of autoimmune antibodies in pregnancy loss[J]. Journal of Gansu University of Traditional Chinese Medicine,2023,40(02):51-56.
[25] Zhang Xiaofen. Research progress on factors affecting embryonic termination[J]. Electronic Journal of Practical Clinical Nursing,2020,5(26):190.
[26] Cai Xiaoru, Chen Xuxuan, Cai Xiaozhu. Analysis of clinical characteristics and influencing factors of 98 cases of maternal embryonic arrest[J]. Clinical Medical Engineering,2022,29(3):421-422.
[27] Wang Ying. Exploring risk factors for embryonic foetal termination in living and working environments[J]. China Medical Guide,2017,15(33):148-149.
[28] Zhao Xiaojuan, Wei Ke, Dong Fei, et al. Analysis of the incidence and influencing factors of 8693 cases of embryonic termination in women of childbearing age[J]. Hainan Medicine,2023,34(14):2075-2078. 
[29] Li Jun. Analysis of factors affecting embryonic arrest in pregnant women in early pregnancy[J]. Modern Diagnosis and Treatment,2021,32(4):590-591.
[30] Feng Xiaoyue, Chen Liwen, Wu Huichen et al. Analysis of high-risk factors for early pregnancy embryonic arrest[J]. China Drugs and Clinics,2021,21(23):3852-3855.
[31] Yan Cuiyan,Li Jian. Investigation of psychological status and analysis of influencing factors in women with embryo termination[J]. Chinese Journal of Family Planning,2018,26(8):665-668,682.
[32] Wang Zhenqing,Guo Yue,Wu Xue. A study on the relationship between anxiety, depression and social support in patients with recurrent immune embryonic arrest[J]. Journal of Nursing Management,2018,18(5):324-327.
[33] Han Tingting. Early embryonic arrest is not a cause for concern for pregnant mothers[J]. Family medicine, 2023, (09):12.
[34] Huang Ling-Jia; Yang Shu-Qi; Sun Xin; Huang Ming-Li. Research progress on the influencing factors related to embryonic termination from the perspective of molecular biology[J]. Chinese Journal of Reproductive Health, 2021, 32(01): 79-82.
[35] Zhu Hongrong. Methods of reducing embryonic termination[J]. Health for all,2023,(22):48-49.
[36] Yu Gongzhi; Cao Ming; Cheng Wenna; Lu Huihui; Zhou Yan. A study on the effects of adverse maternal history on anxiety and depression in pregnant women[J]. Journal of Jianghan University (Natural Science Edition),2023,51(04):79-86.
[37] Zhou Qing, Liu Shuaimei, Zhang Ruijin et al. Progress in the study of factors associated with embryonic termination [J]. China Medicine Herald,2019,16(23):53-56.

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