Advances in the pathogenesis of vestibular migraine-associated anxiety and depression

Yide Hao; Zhengquan Lei; Mengyao Gong

doi:10.23977/medcm.2024.060307

Advances in the pathogenesis of vestibular migraine-associated anxiety and depression

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DOI: 10.23977/medcm.2024.060307 | Downloads: 4 | Views: 99

Author(s)

Yide Hao ¹, Zhengquan Lei ², Mengyao Gong ¹

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, 712046, China
² Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, 712000, China

Corresponding Author

Zhengquan Lei

ABSTRACT

The common symptoms of vestibular migraine (VM) are spontaneous or positional vertigo attacks accompanied by migraine, and anxiety and depression are prone to be a common clinical concomitant. VM-associated anxiety and depression disorders are interconnected with the clinical symptoms of VM, which mainly involves functional changes such as paroxysmal vertigo and vestibular abnormalities, and is affected by gender and attack frequency. Impact. Vertigo-anxiety loops of action, periaqueductal grey matter, and adrenocorticotropic hormone-releasing factor serve as anatomical and physiological bases of VM-related anxiety and depression, and abnormal release of neurotransmitters such as norepinephrine (NA), 5-hydroxytryptophan (5-HT), and dopamine (DA) may ultimately lead to the development of VM-related cognitive deficits. Acupuncture therapy, cognitive-behavioural therapy and drugs may have a therapeutic effect on VM-related anxiety and depression.

KEYWORDS

Vestibular migraine; anxiety and depression; pathogenesis

CITE THIS PAPER

Yide Hao, Zhengquan Lei, Mengyao Gong, Advances in the pathogenesis of vestibular migraine-associated anxiety and depression. MEDS Chinese Medicine (2024) Vol. 6: 47-54. DOI: http://dx.doi.org/10.23977/medcm.2024.060307.

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Advances in the pathogenesis of vestibular migraine-associated anxiety and depression

Author(s)

Affiliation(s)

Corresponding Author

ABSTRACT

KEYWORDS

CITE THIS PAPER

REFERENCES

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