Author(s)

Xiao Liu ¹, Ruiyang Sun ¹, Ruixue Ma ¹, Xia Wang ¹

Affiliation(s)

¹ Department of Maternal and Child Health, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxi Road, Jinan, 250012, China

Corresponding Author

Xia Wang

ABSTRACT

This study presents an assessment of the global breast cancer burden from 1990 to 2019, highlighting the current status and the impact of metabolic factors. Data on breast cancer incidence, deaths, disability-adjusted life years (DALYs), and the age-standardized rate in 204 countries and regions and its metabolic factors were obtained from the Global Burden of Disease Study 2019. The estimated annual percentage change (EAPC) was used to quantify the temporal trends. In 2019, the incidence cases of breast cancer globally reached 202,354, deaths reached 700,660. The age-standardized incidence rate (ASIR) of breast cancer globally increased by 0.33, while the age-standardized rates of deaths (ASMR) and DALYs decreased with EAPC of -0.56 and -0.5, respectively. In 2019, the EAPC in ASIR was negatively correlated with socio-demographic index (R = -0.21, P < 0.01). High fasting plasma glucose and high body mass index were the primary risk factors for breast cancer. Overall, the global burden of breast cancer is substantial, indicating the need for targeted prevention and control measures.

KEYWORDS

Breast cancer, Disease burden, Metabolic Factors, Estimated annual percentage change

CITE THIS PAPER

Xiao Liu, Ruiyang Sun, Ruixue Ma, Xia Wang, Global Burden of Breast Cancer and the Impact of Metabolic Factors from 1990 to 2019: Based on the Global Burden of Disease Study 2019. MEDS Public Health and Preventive Medicine (2024) Vol. 4: 123-130. DOI: http://dx.doi.org/10.23977/phpm.2024.040217.

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