Study on the application and mechanism of action of Ling Gui Zhu Gan Tang in heart failure

Ao Xu; Congcong Yu; Ke Zhao; Panpan He; Zhengfang Zhou; Peng Lei

doi:10.23977/medcm.2024.060408

Study on the application and mechanism of action of Ling Gui Zhu Gan Tang in heart failure

Download as PDF

DOI: 10.23977/medcm.2024.060408 | Downloads: 17 | Views: 640

Author(s)

Ao Xu ¹, Congcong Yu ¹, Ke Zhao ¹, Panpan He ¹, Zhengfang Zhou ¹, Peng Lei ^1,2

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
² The First Clinical Medical College of Shaanxi University of Chinese Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China

Corresponding Author

Peng Lei

ABSTRACT

Ling Gui Zhu Gan Tang is a classic formula from Zhang Zhongjing's "Treatise on Miscellaneous Diseases of Typhoid", which has been highly respected by medical practitioners of all times, and is often used in the treatment of cardiovascular diseases in modern times, especially in the treatment of heart failure.The dection has a remarkable therapeutic effect. In recent years, with the in-depth research, some of the mechanisms of ling gui zhu gan tang have been proved, and the article provides an overview on the application of ling gui zhu gan tang and the mechanism of its effect. So that it can provide theoretical guidance and data support for the in-depth research of this formula. The application and mechanism of action of Ling Gui Zhu Gan Tang are reviewed in this article to provide theoretical guidance and data support for the in-depth study of this formula.

KEYWORDS

Ling Gui Zhu Gan Tang; heart failure; pharmacological study; clinical application; mechanism of action

CITE THIS PAPER

Ao Xu, Congcong Yu, Ke Zhao, Panpan He, Zhengfang Zhou, Peng Lei, Study on the application and mechanism of action of Ling Gui Zhu Gan Tang in heart failure. MEDS Chinese Medicine (2024) Vol. 6: 58-64. DOI: http://dx.doi.org/10.23977/medcm.2024.060408.

REFERENCES

[1] Liu Mingbo, He Xinye, Yang Xiaohong, et al. Interpretation of key points in the China Cardiovascular Health and Disease Report 2023[J]. Chinese Family Medicine:1-19.
[2] Zhou Yuan, Li Qizhu, Xu Jingyu. Research progress of Ling Gui Zhu Gan Tang in the treatment of heart failure [J]. Shaanxi Traditional Chinese Medicine, 2022,43(12):1819-1821.
[3] Jiang Deyou, Zhang Wanqiu, Han Jieru. Research progress of Ling Gui Zhu Gan Tang[J]. Journal of Chinese Medicine, 2021,36(12):2562-2567.DOI:10.16368/j.issn.1674-8999.2021.12.531.
[4] Ge Junbo, Lin Guowei, Wang Jiyao. Practical internal medicine [M]. Beijing: People's Health Press, 2018: 818.
[5] Xu Dingli, Song Lin. Interpretation of the Chinese Guidelines for the Diagnosis and Treatment of Heart Failure 2024[J]. Journal of Clinical Cardiovascular Disease, 2024,40(06):437-439.DOI:10.13201/j. issn.1001-1439. 2024.06. 002.
[6] Chinese Journal of Cardiovascular Disease Editorial Board Chinese Medical Association Division of Cardiovascular Diseases Chinese Physicians Association of Cardiovascular Physicians Branch Chinese Physicians Association of Heart Failure Specialty Committee. Chinese guidelines for the diagnosis and treatment of heart failure 2024[J]. Chinese Journal of Cardiovascular Disease, 2024.
[7] Lan Yu, Luo Fukun, Yu Yue, et al. Traditional Chinese medicine understanding of heart failure and treatment strategy of meridian prescription[J]. Chinese Journal of Traditional Chinese Medicine:1-14.DOI:10.19540/j. cnki. cjcmm. 20240814.501.
[8] Chen Hao, Xu Fafei, Han Jingbo. Research progress of Chinese medicine in the treatment of chronic heart failure [J]. Research on Traditional Chinese Medicine, 2022,35(06):88-92.
[9] Ye Qing, Liu Dongsheng, Wang Lanxia, et al. Progress of research on chemical composition, pharmacological effect and quality control of Poria[J]. Chinese Medicine Information, 2023,40(02):75-79.DOI:10.19656/j. cnki. 1002-2406. 20230214.
[10] Li Xue, Zhao Jinghan, Wu Wenxuan, et al. Progress in the study of chemical composition and pharmacological effects of Gui Zhi[J]. Journal of Traditional Chinese Medicine, 2023,51(05):111-114.DOI:10.19664/j.cnki. 1002-2392. 230114.
[11] LI Jing, HE Mou, LI Ling, et al. Progress on the chemical composition and pharmacological effects of the volatile oil of Atractylodes macrocephala[J]. Chinese patent medicine, 2024,46(03):881-889.
[12] XIE Ruiqiang, WANG Changfu. Progress in the study of chemical composition and pharmacological effects of Radix et Rhizoma Glycyrrhizae[J]. Chinese Medicine Information, 2023,40(04):84-89.DOI:10.19656/j.cnki. 1002-2406. 20230414.
[13] Cheng Qian, Zhou Qingwei, Xue Jiaxi, et al. Research progress on modern clinical application and mechanism of Linggui Zhugan Decoction [J/OL]. Journal of Liaoning University of Traditional Chinese Medicine, 1-8 [2024-11-07]. http://kns.cnki.net/kcms/detail/21.1543.R.20241015.0952.008.html
[14] Zhang Sheng'an, Liu Zhidong, Dai Liang, et al. Clinical application of Ling Gui Zhu Gan Tang: 1 systematic evaluation and Meta-analysis[J]. Chinese Herbal Medicine, 2023,54(14):4599-4614.
[15] Zhao LL. Effects of linggui juguangan soup on serum inflammatory factors, lipids and oxidation levels in patients with coronary heart disease[J]. Chinese Community Physician, 2020,36(16):83-84.
[16] HU Shuangxuan, LI Xiangzhong. Clinical efficacy and effect on LVEF of Ling Gui Zhu Gan Tang plus reduction in the treatment of chronic heart failure in the elderly[J]. Heilongjiang Traditional Chinese Medicine, 2020, 49(05): 10-11.
[17] Wang Xiang, Mo Jiajia, Tang Tongjuan, et al. Exploration of the effects and mechanisms of linggui juguangan tang in improving myocardial infarction-induced heart failure in rats based on Nrf2/BNIP3 pathway[J]. Chinese Journal of Pharmacology, 2023,39(12):2390-2397.

Subscription

E-Mail Alert

Downloads:	8498
Visits:	476276

Study on the application and mechanism of action of Ling Gui Zhu Gan Tang in heart failure

Author(s)

Affiliation(s)

Corresponding Author

ABSTRACT

KEYWORDS

CITE THIS PAPER

REFERENCES

RESOURCES

JOIN US

PUBLICATION SERVICES

CONTACT US