Author(s)

Weilin Yang ¹, Xianjie Zhang ¹, Yanhua Peng ¹, Lei Deng ²

Affiliation(s)

¹ Department of Anesthesiology, The Deyang People's Hospital, Deyang, Sichuan, China
² Department of Gastroenterology, The Deyang People's Hospital, Deyang, Sichuan, China

Corresponding Author

Lei Deng

ABSTRACT

This study is designed to explore the correlation between insomnia and alcohol intake frequency via a Mendelian randomization study. Data for Mendelian randomization analysis were obtained from the IEU Open GWAS project. GWAS datasets for insomnia and alcohol intake frequency were used to conduct the analysis. The random-effects inverse-variance weighted method was used in the main MR analyses and the weighted median method as complementary analyses. MR-Egger, weighted mode, and simple mode were also adopted to assess causal relationships between exposure and outcome variables. Sensitivity analysis proved the reliability of the analysis results. There was no positive relationship between insomnia and alcohol intake frequency. 

KEYWORDS

Insomnia, alcohol intake frequency, Mendelian randomization

CITE THIS PAPER

Weilin Yang, Xianjie Zhang, Yanhua Peng, Lei Deng, Research on the correlation between insomnia and alcohol intake frequency: a Mendelian randomization study. MEDS Clinical Medicine (2025) Vol. 6: 26-31. DOI: http://dx.doi.org/10.23977/medsc.2025.060204.

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