Author(s)

Lina Shang ¹

Affiliation(s)

¹ The Affiliated Hospital of Hebei University, Baoding, Hebei, China

Corresponding Author

Lina Shang

ABSTRACT

The Objective is to analyze the causes of misdiagnosis in thyroid nodules during ultrasonographic diagnosis. Thirty cases of thyroid nodules, initially diagnosed by ultrasonography but subsequently confirmed as misdiagnosed by postoperative pathology between January 2024 and December 2024, were included. Ultrasonographic features, pathological findings, and clinical information were analyzed to classify types of misdiagnosis and summarize the underlying causes. Among the 30 misdiagnosed cases, 15 (50%) were benign nodules misdiagnosed as malignant, with adenomas being the most frequently misdiagnosed as papillary carcinoma (8 cases). Ten cases (33.3%) were malignant nodules misdiagnosed as benign, predominantly involving missed diagnoses of micropapillary carcinoma (6 cases). Three cases (10%) involved misjudgment of nodule nature, and 2 cases (6.7%) were missed diagnoses of multiple nodules. The primary underlying causes of misdiagnosis included atypical ultrasonographic features, inadequate equipment resolution, insufficient operator expertise, and poor integration of clinical information. Misdiagnosis of thyroid nodules in ultrasonographic diagnosis is associated with the complex characteristics of nodules, technical limitations, and operators’ subjective judgment. Improving diagnostic accuracy requires the application of high-resolution ultrasound technology, enhanced operator training, integration of multidisciplinary clinical information, and dynamic follow-up of suspicious nodules.

KEYWORDS

Thyroid nodules, Ultrasonographic diagnosis, Causes of misdiagnosis

CITE THIS PAPER

Lina Shang, Analysis of Causes of Misdiagnosis in Thyroid Nodules by Ultrasonographic Diagnosis. MEDS Clinical Medicine (2025) Vol. 6: 23-26. DOI: http://dx.doi.org/10.23977/medsc.2025.060405.

REFERENCES

[1] Ding Baocheng. Clinical efficacy and accuracy of color Doppler ultrasound in diagnosing thyroid nodules[J]. Modern Medical Imagelogy, 2025, 34 (03): 540-543.
[2] Zhang Wenjin, He Nian'an. Value of contrast-enhanced ultrasound in differentiating thyroid TI-RADS category 4 nodules [J]. Anhui Medical Journal, 2025, 46 (03): 339-344.
[3] Shao Chunhui, Li Peiying, Zhao Junzhi, et al. The value of multimodal ultrasound in the diagnosis of C-TIRADS4 fine needle aspiration cytology for TBSRTC Type Ⅲ thyroid nodules[J]. Chinese Journal of General Practice, 2025, 23 (03): 464-467,484. 
[4] Wu Zhouli. Application value of ultrasound in differentiating thyroid nodules - A review of "Advanced Interpretation of Thyroid Ultrasound" [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2025, 31 (08): 319.
[5] Zhang Nan. The clinical value of high-frequency ultrasound in the differential diagnosis of benign and malignant thyroid nodules [J]. Chinese Typical Case Database, 2025, 19 (01): 135-138.

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