Author(s)

Conner Lv ¹, Donald Moore ¹, Doris Dai ¹

Affiliation(s)

¹ Eternal Grace Pte. Ltd, Tuas, Singapore

Corresponding Author

Conner Lv

ABSTRACT

This randomized, double-blind, controlled trial aimed to explore the effects of DHA-enriched fish oil alone or combined with galangal extract on memory and attention in adolescents. A total of 68 adolescents aged 12-18 years were recruited, with 66 completing the 90-day intervention. They were divided into four groups: high-dose combo group (HCG, 600 mg fish oil plus galangal extract daily), high-dose group (HG, 600 mg fish oil daily), low-dose group (LG, 300 mg fish oil daily), and control group (CG, placebo). Participants took the test product for 90 consecutive days, and their attention and memory levels were assessed using the sub-item memory scales and MQ task and the IQ test at baseline (D0), day 30 (D30), and day 90 (D90). Repeated-measures analysis of variance revealed that the combined intervention group exhibited significant improvements in all core memory subscale scores and MQ values. Specifically, at D30, the HCG showed marked increases in all memory subscale scores (P<0.01 or P<0.001), with further prominent enhancements at D90 (all P<0.001). The single-intervention groups (HG and LG) showed moderate improvements in partial memory subscale scores at D30 (P<0.05) and D90 (P<0.05 or P<0.01), but these improvements were significantly weaker than those in the combined intervention group (all P<0.05 at D90).The control group showed no significant changes in any memory or cognitive outcomes (all P>0.05). No significant changes in IQ-related indicators were observed in the CG, LG, and HG (all P>0.05), while the HCG showed significant improvements in key IQ dimensions at D30 (P<0.05 or P<0.01) and D90 (all P<0.01). These findings support that DHA combined with galangal extract improves attention, memory, and decision-execution accuracy in adolescents, and further enhances key IQ-related cognitive functions contributing to cognitive health management. Over the 90-day period, the effects of DHA combined with galangal extract were significantly superior to those of the other three groups.

KEYWORDS

Omega-3, DHA, Alpinia galanga (L.) Willd, Memory, Attention, Adolescents

CITE THIS PAPER

Conner Lv, Donald Moore, Doris Dai. Randomized, Double-Blind, Controlled Trial of Memory and Attention Enhancement in Adolescents via DHA-Enriched Fish Oil Combined with Galangal Extract. Social Medicine and Health Management (2026). Vol. 7, No.1, 24-31. DOI: http://dx.doi.org/10.23977/socmhm.2026.070103.

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