Author(s)

Zhang Jun ¹, Lin Guodong ¹, Lin Wenxi ¹, Huang Wei ¹, Xie Yingying ¹

Affiliation(s)

¹ Chengde Hospital of Traditional Chinese Medicine, Chengde, Hebei Province, 067000, China

Corresponding Author

Xie Yingying

ABSTRACT

This article observes the clinical effect and safety of silk fibroin dressing for wound healing of atrophic acne scars after CO2 fractional laser. A total of 100 patients were randomly divided into an observation group and a control group, with 50 cases in each group. After the laser surgery, the observation group used silk fibroin dressing (Fuxiang Sitai Medical Technology), and the control group used hyaluronic acid (HA) dressing. The indications of these two dressings are non-chronic wounds, including suture wounds after surgery and lasersurgery. The wound healing times were recorded. The results showed that the scab forming time (1.76±0.55 days vs 2.79±0.58 days), scab peeling time (4.35±0.66 days vs 6.31±1.24 days), and total wound healing time (3.51±0.52 days vs 5.18 ± 0.77 days) in the observation group were significantly shorter than those in the control group (P<0.05). At the same time, the Visual Analog Scale (VAS) pain score (1.24 ± 0.67 vs 3.54 ± 0.54) and Vancouver Scar Scale (VSS) score (5.31 ± 0.68 vs 8.63 ± 0.93) in the observation group were significantly lower than the control group (P<0.05). The adverse reaction rate in the observation group was 6.00% (3/50), which was significantly lower than 18.00% (9/50) in the control group (x2=10.733, P<0.01). In conclusion, the application of silk fibroin dressing can speed up tissue healing, reduce pain, improve scars, and lower the adverse reaction rate after CO2 fractional laser surgery.

KEYWORDS

Silk fibroin dressing; Fractional laser; Wound repair; Acne scars; Vancouver Scar Scale

CITE THIS PAPER

Zhang Jun, Lin Guodong, Lin Wenxi, Huang Wei, Xie Yingying. Application of Silk Fibroin Dressing in Wound Repair after Laser Surgery. Social Medicine and Health Management (2026). Vol. 7, No.1, 83-87. DOI: http://dx.doi.org/10.23977/socmhm.2026.070111.

REFERENCES

[1] Zhang J, Xu F, Lin H, et al. Efficacy of fractional CO2 laser therapy combined with hyaluronic acid dressing for treating facial atrophic acne scars: a systematic review and meta-analysis of randomized controlled trials[J]. Lasers in medical science, 2023, 38(1): 214.
[2] Liu F, Zhou Q, Tao M, et al. Efficacy and safety of CO2 fractional laser versus Er: YAG fractional laser in the treatment of atrophic acne scar: A meta‐analysis and systematic review[J]. Journal of Cosmetic Dermatology, 2024, 23(9): 2768-2778.
[3] Ding Y W, Wang Z Y, Ren Z W, et al. Advances in modified hyaluronic acid-based hydrogels for skin wound healing[J]. Biomaterials science, 2022, 10(13): 3393-3409.
[4] Mazurek Ł, Szudzik M, Rybka M, et al. Silk fibroin biomaterials and their beneficial role in skin wound healing[J]. Biomolecules, 2022, 12(12): 1852.
[5] Liu X, Chen K, Zhao X, et al. Current research status and progress of laser therapy in wound healing[J]. Plastic and Aesthetic Research, 2026, 13: 10.
[6] Rodrigues M, Ayala-Cortés A S. Post-inflammatory hyperpigmentation[M]//Pigmentary Skin Disorders. Cham: Springer International Publishing, 2018: 197-208.

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