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Risk Prediction Models for Prevention of Complications in Medical and Surgical Nursing: A Narrative Review of Pressure Injury, Venous Thromboembolism, Falls and Postoperative Delirium

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DOI: 10.23977/medsc.2026.070311 | Downloads: 3 | Views: 92

Author(s)

Yumei Liu 1

Affiliation(s)

1 Ningqiang County Hospital of Traditional Chinese Medicine, Hanzhong, Shaanxi, 724400, China

Corresponding Author

Yumei Liu

ABSTRACT

Hospital-acquired complications remain major threats to patient safety and quality of nursing care. Pressure injury, venous thromboembolism, inpatient falls, and postoperative delirium are common among medical and surgical patients, particularly older adults, critically ill patients, postoperative patients, immobile patients, and those with multimorbidity. Traditional nursing risk assessment relies largely on clinical judgment and standardized scales, which are useful but may be insufficient for dynamic and individualized risk prediction. Recent studies have increasingly explored electronic health record-based models, artificial intelligence, machine learning, clinical decision support systems, and specialty-specific prediction tools to identify high-risk patients earlier and guide targeted nursing interventions. This review summarizes current progress in nursing-relevant risk prediction models for common medical and surgical complications, discusses their clinical application in pressure injury, venous thromboembolism, falls, and delirium prevention, and highlights methodological and implementation challenges. It further emphasizes that prediction models should not be treated as isolated statistical tools, but as part of a practical nursing safety system that connects risk identification with bedside decision-making, patient education, intervention delivery, outcome monitoring, and continuous quality improvement. Future nursing research should move from model development alone toward closed-loop systems that integrate prediction, alerting, stratified intervention, outcome evaluation, and workflow optimization. 

KEYWORDS

Risk prediction; nursing safety; pressure injury; venous thromboembolism; inpatient falls; postoperative deliriumt

CITE THIS PAPER

Yumei Liu. Risk Prediction Models for Prevention of Complications in Medical and Surgical Nursing: A Narrative Review of Pressure Injury, Venous Thromboembolism, Falls and Postoperative Delirium. MEDS Clinical Medicine (2026). Vol. 7, No. 3, 75-86. DOI: http://dx.doi.org/10.23977/medsc.2026.070311.

REFERENCES

[1] Padula WV, Armstrong DG, Pronovost PJ, et al. Predicting pressure injury risk in hospitalised patients using machine learning with electronic health records: a US multilevel cohort study [J]. BMJ Open. 2024;14(4):e082540.
[2] Braden BJ. The Braden Scale for Predicting Pressure Sore Risk: Reflections after 25 years [J]. Adv Skin Wound Care. 2012;25(2):61.
[3] Guo YF, Zhang D, Chen Y, et al. Integrating D-Dimer Thresholds into the Revised Caprini Risk Stratification to Predict Deep Vein Thrombosis Risk in Preoperative Knee Osteoarthritis Patients [J]. Clin Appl Thromb Hemost. 2025;31:10760296241311265.
[4] Parsons R, Blythe R, Cramb S, et al. An Electronic Medical Record-Based Prognostic Model for Inpatient Falls: Development and Internal-External Cross-Validation [J]. J Med Internet Res. 2024;26:e59634.
[5] Qin C, Hu S, Lu J, et al. Developing a Pressure Injury Predictive Indicator System for Data Mining in Health Care Information Systems: A Sequential Mixed-Methods Study [J]. Advances in Skin & Wound Care. 2025;38(9):E90-E97.
[6] Cho I, Cho J, Hong JH, et al. Utilizing standardized nursing terminologies in implementing an AI-powered fall-prevention tool to improve patient outcomes: a multihospital study [J]. J Am Med Inform Assoc. 2023;30(11):1826-1836.
[7] Tu Y, Zhu H, Zhang X, et al. Machine learning-based prediction models for postoperative delirium: a systematic review and meta-Analysis [J]. BMC Psychiatry. 2025;25(1):940.
[8] Visconti AJ, Sola OI, Raghavan PV. Pressure Injuries: Prevention, Evaluation, and Management [J]. Am Fam Physician. 2023;108(2):166-174.
[9] Serpa LF, Santos VL, Peres GR, et al. Validity of the Braden and Waterlow subscales in predicting pressure ulcer risk in hospitalized patients [J]. Appl Nurs Res. 2011;24(4):e23-e28.
[10] Alderden J, Drake K P, Wilson A, et al. Hospital acquired pressure injury prediction in surgical critical care patients [J]. BMC Med Inform Decis Mak. 2021, 21(1):12.
[11] Zhou L, Hu Y, Ma D, et al. Best Evidence Summary for the Prevention of Pressure Injuries in Orthopaedic Patients [J]. J Clin Nurs. 2024;33(12):4651-4664.
[12] Marshall V, Qiu Y, Jones A, et al. Hospital-acquired pressure injury prevention in people with a BMI of 30.0 or higher: A scoping review [J]. J Adv Nurs. 2024;80(4):1262-1282.
[13] Reese TJ, Domenico HJ, Hernandez A, et al. Implementable Prediction of Pressure Injuries in Hospitalized Adults: Model Development and Validation [J]. JMIR Med Inform. 2024;12:e51842.
[14] Šín P, Hokynková A, Marie N, et al. Machine Learning-Based Pressure Ulcer Prediction in Modular Critical Care Data [J]. Diagnostics (Basel). 2022;12(4):850.
[15] Kottner J, Cuddigan J, Carville K, et al. International pressure injury clinical guideline [J]. J Tissue Viability. 2019;28:51-58.
[16] Yuan X, Zhu L, Jiang K, et al. Impact of Artificial Intelligence-Assisted Closed-Loop Mobile Nursing Information Management on Nursing Quality Indicators and Work Efficiency [J]. Risk Manag Healthc Policy. 2025;18:3581-3591.
[17] Bassa B, Little E, Ryan D, et al. VTE rates and risk factors in major trauma patients [J]. Injury. 2024;55(12):111964.
[18] Xiang X, Yu Y, Fang X, et al. Best evidence summary on anticoagulant management in patients with cancer-associated venous thromboembolism [J]. Asia Pac J Oncol Nurs. 2025;12:100345.
[19] Zhou M, Wang R, Zhu L, et al. Risk Assessment of Venous Thromboembolism in Neurocritical Patients: Construction and Validation of a Clinical Prediction Model [J]. Mediators Inflamm. 2025;2025:8133560.
[20] Zhang Z, Xu S, Song M, et al. Machine learning-based prediction model and web calculator for postoperative LDVT in colorectal cancer [J]. Front Oncol. 2025;15:1673705.
[21] Ge WJ, Zhu TF, Zhu XY, et al. Systematic review of a machine learning model for prediction of venous thromboembolism risk[J]. Thromb Res. 2025;256:109507.
[22] Tolera BD, Gebremedhin KB. Nurses' knowledge and practice regarding venous-thromboembolism prevention in tertiary hospitals of Addis Ababa, Ethiopia: A cross-sectional study[J]. J Vasc Nurs. 2024;42(2):123-130.
[23] Raya-Benítez J, Heredia-Ciuró A, Calvache-Mateo A, et al. Effectiveness of non-instrumental early mobilization to reduce the incidence of deep vein thrombosis in hospitalized patients: A systematic review and meta-analysis [J]. Int J Nurs Stud. 2025;161:104917.
[24] Kang CW, Yan ZK, Tian JL, et al. Constructing a fall risk prediction model for hospitalized patients using machine learning [J]. BMC Public Health. 2025;25(1):242.
[25] González-Castro A, Leirós-Rodríguez R, Prada-García C, et al. The Applications of Artificial Intelligence for Assessing Fall Risk: Systematic Review [J]. J Med Internet Res. 2024;26:e54934.
[26] Shim S, Yu JY, Jekal S, et al. Development and validation of interpretable machine learning models for inpatient fall events and electronic medical record integration [J]. Clin Exp Emerg Med. 2022;9(4):345-353.
[27] Cai S, Li J, Gao J, et al. Prediction models for postoperative delirium after cardiac surgery: Systematic review and critical appraisal [J]. Int J Nurs Stud. 2022;136:104340.
[28] Chen J, Yu J, Zhang A. Delirium risk prediction models for intensive care unit patients: A systematic review [J]. Intensive Crit Care Nurs. 2020;60:102880.
[29] Li J, Fan Y, Luo R, et al. The Impact of Non-Pharmacological Sleep Interventions on Delirium Prevention and Sleep Improvement in Postoperative ICU Patients: A Systematic Review and Network Meta-Analysis [J]. Intensive Crit Care Nurs. 2025;87:103925.
[30] da Silva JLS, Azi L, Ding K, et al. Nonpharmacological Interventions Prevent Delirium in Older Adult Surgical Patients: A Network Meta-Analysis of Randomized Controlled Trials [J]. J Gerontol Nurs. 2025;51(9):20-29.
[31] Matsumoto K, Nohara Y, Sakaguchi M, et al. Temporal Generalizability of Machine Learning Models for Predicting Postoperative Delirium Using Electronic Health Record Data: Model Development and Validation Study [J]. JMIR Perioper Med. 2023;6:e50895.
[32] Wang YY, Yue JR, Xie DM, et al. Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and Function in Older Adults: A Randomized Clinical Trial [J]. JAMA Intern Med. 2020;180(1):17-25.
[33] Zhang WG, Liu JW, Yang SY, et al. A Study on the Improvement of Nursing Interruption Risk by a Closed-Loop Management Model [J]. Risk Manag Healthc Policy. 2021;14:2945-2952.
[34] Dhannoon A, Teklay S, Caddick J, et al. 752 VTE Prophylaxis and VTE Assessment Form in Plastic Surgery: A Closed-Loop Audit [J]. British Journal of Surgery. 2024;111(6):znae63.261.
[35] Gleim P, Ritzi A, Mählmann S, et al. Participatory Design of an AI-Based CDSS for Delirium Prevention [J]. Stud Health Technol Inform. 2025;327:402-403.
[36] Nieboer D, van der Ploeg T, Steyerberg EW. Assessing Discriminative Performance at External Validation of Clinical Prediction Models [J]. PLoS One. 2016;11(2):e0148820.
[37] Pérez PE, Oliveira AC. How to quantify the qualitative aspects of nursing outcomes classification scales with psychosociocultural indicators[J]. Rev Esc Enferm USP. 2013;47(3):728-735.
[38] Gao S, Albu E, Stijnen P, et al. Comparing methods for handling missing data in electronic health records for dynamic risk prediction of central-line associated bloodstream infection [J]. BMC Med Res Methodol. 2026;26(1):128.
[39] Baniecki H, Sobieski B, Szatkowski P, et al. Interpretable machine learning for time-to-event prediction in medicine and healthcare [J]. Artif Intell Med. 2025;159:103026.
[40] Lee TC, Shah NU, Haack A, et al. Clinical Implementation of Predictive Models Embedded within Electronic Health Record Systems: A Systematic Review [J]. Informatics (MDPI). 2020;7(3):25.
[41] Lei J, Guan P, Gao K, et al. Characteristics of health IT outage and suggested risk management strategies: an analysis of historical incident reports in China [J]. Int J Med Inform. 2014;83(2):122-130.

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