Anti-Cardiovascular Effects of Diosgenin and Its Related Derivatives
DOI: 10.23977/medsc.2021.020103 | Downloads: 3 | Views: 65
Yingfeng Xue 1, Jiayan Lin 1, Hongbo Zhang 1, Fuyao Xiao 1, Weigang Li 1, Nannan Huang 1
1 Heilongjiang University of Chinese Medicine, Harbin 150040, China
Corresponding AuthorNannan Huang
Research has found that diosgenin can play a pharmacological role in anti-thrombotic, anti-atherosclerotic, anti-inflammatory, anti-hyperlipidemic, anti-hypertensive, etc. The derivatives synthesized from diosgenin: diosgenin prodrugs, diosgenin amine derivatives, diosgenin acyl derivatives also show anti-thrombotic, anti-inflammatory, and enhanced pharmacological effects. Therefore, they can exert a wide range of inhibitory effects on cardiovascular diseases, which are a serious threat to human health. Based on this, this article discusses the anti-cardiovascular disease effects of diosgenin and the above derivatives, aiming to lay the foundation for the deeper research and application of diosgenin and its derivatives against cardiovascular diseases.
KEYWORDSDiosgenin, Cardiovascular disease, Diosgenin derivatives, Pharmacological effects
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Yingfeng Xue, Jiayan Lin, Hongbo Zhang, Fuyao Xiao, Weigang Li and Nannan Huang. Research on Role of Regulatory Polypeptide Ac-Sdkp in Restraining Silicosis Fibrosis. MEDS Clinical Medicine (2021) 2: 10-14. DOI: http://dx.doi.org/10.23977/medsc.2021.020103.
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