Author(s)

Sun Wei ¹, WU Qiao ¹

Affiliation(s)

¹ Department of Psychiatry, the Third People's Hospital of Mianyang, Mianyang, Sichuan, 621000, China

Corresponding Author

WU Qiao

ABSTRACT

Objective To study the relationship between serum interleukin 6 (IL-6) and sustained attention in patients with alcohol use disorders( AUD )and provide evidence for improving the sustained attention of patients with AUD. Methods Forty-seven patients with AUD and 47 healthy patients from May 2020 to October 2020 in Mental Hospital of Yunan Province were selected as the study group and the control group. The IL-6 and the visual and auditory attentional performance test (IVA-CPT) were compared between the two groups, and the relationship between IL-6 and IVA-CPT in AUD patients was analyzed by Pearson's linear correlation method. Results The IL-6 of the study group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). The correct number of IVA-CPT in the study group was significantly lower than that of the control group, and the number of errors, omissions, and response time of IVA-CPT were significantly higher than those of the control group. The differences were statistically significant (P<0.05). According to the analysis of Pearson linear correlation method, there is no correlation between IL-6 and IVA-CPT correct number, error number, and missed number (P>0.05). IL-6 and IVA-CPT reaction time are negatively correlated (P<0.05). Conclusion The IL-6 of patients with AUD has a certain relationship with sustained attention. Clinically, the level of IL-6 can be reduced to improve the sustained attention of patients with AUD.

KEYWORDS

Alcohol use disorders il-6, Sustained attention, Iva-cpt correct number, Reaction time

CITE THIS PAPER

Sun Wei, WU Qiao, The Relationship between Serum Interleukin-6 and Sustained Attention in Patients with Alcohol Use Disorders. MEDS Chinese Medicine (2021) 3: 138-142. DOI: http://dx.doi.org/10.23977/medcm.2021.030229

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