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Research progress of traditional Chinese medicine in regulating Th17 / Treg balance in asthma

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DOI: 10.23977/medsc.2022.030201 | Downloads: 10 | Views: 829

Author(s)

Anlai Liu 1, Jinghong Shi 1

Affiliation(s)

1 Shaanxi University of traditional Chinese Medicine

Corresponding Author

Jinghong Shi

ABSTRACT

In recent years, as people's research on the two newly discovered helper T cells-Th17 and Treg has become more and more in-depth, the imbalance between the two is generally believed to be involved in inflammatory diseases, especially in the onset of bronchial asthma. To a more to a more critical role, therefore, the regulation of its balance is considered to be a new target for the treatment of asthma. Due to the multi-target characteristics of traditional Chinese medicine, it has broad application prospects when targeting the complex Th17/Treg imbalance. Through a review of the literature over the past ten years, this article shows that traditional Chinese medicine can affect the differentiation of Th17 and Treg by Through a review of the literature over the past ten years, this article shows that traditional Chinese medicine can affect the differentiation of Th17 and Treg by regulating the expression of IL-6, TGF-β, FOXP3, and STAT3, thereby restoring the balance of Th17/Treg. Purpose, so as to achieve the purpose of alleviating airway reactions and treating asthma.

KEYWORDS

Traditional Chinese medicine, asthma, Th17 / Treg imbalance

CITE THIS PAPER

Anlai Liu, Jinghong Shi, Research progress of traditional Chinese medicine in regulating Th17 / Treg balance in asthma. MEDS Clinical Medicine (2022) Vol. 3: 1-7. DOI: http://dx.doi.org/10.23977/medsc.2022.030201.

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