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The Role of Mucosal Immunity in the Pathogenesis of IgA Nephropathy and the Progress of Chinese Medicine Research

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DOI: 10.23977/medsc.2022.030512 | Downloads: 9 | Views: 484

Author(s)

Rongrong Ou 1, Jian Shi 2

Affiliation(s)

1 First Clinical Medical College, Shaanxi University of Traditional Chinese Medicine, Shaanxi, 712046, China
2 Department of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Shaanxi, 710003, China

Corresponding Author

Jian Shi

ABSTRACT

IgA nephropathy (IgAN) is one of the most common pathological types of primary glomerular disease in Asian countries and an important cause of end-stage renal disease. The pathogenesis of IgA nephropathy is still unclear and no specific treatment is available. Recent relevant studies have shown that mucosal immunity is closely related to the pathogenesis of IgA nephropathy, therefore, this article describes the pathogenesis of IgA nephropathy, focusing on the recent progress of mucosal immunity in the pathogenesis of IgA nephropathy.

KEYWORDS

IgA nephropathy, mucosal immunity, pathogenesis, advances in Chinese medicine research

CITE THIS PAPER

Rongrong Ou, Jian Shi, The Role of Mucosal Immunity in the Pathogenesis of IgA Nephropathy and the Progress of Chinese Medicine Research. MEDS Clinical Medicine (2022) Vol. 3: 67-73. DOI: http://dx.doi.org/10.23977/medsc.2022.030512.

REFERENCES

[1] Yu Yusheng, Wang Jinquan. (2006). New perspectives on the clinical aspects of IgA nephropathy and its pathogenesis. Journal of Nephrology and Dialysis Renal Transplantation, no.1, p.60-65.
[2] Wang Qian, Yang Liping, Zhan Yongli. (2018). The role of mucosal immune system in the pathogenesis of IgA nephropathy and the progress of Chinese medicine understanding. Chinese Journal of Integrated Chinese and Western Medicine and Nephrology, vol.19, no.1, p.81-83.
[3] Lai K N. (2012). Pathogenesis of IgA nephropathy. Nat Rev Nephrol, vol.8, no.5, p.275-283.
[4] Chang Sheng, Li Xiaokang. (2020). The Role of Immune Modulation in Pathogenesis of IgA Nephropathy. Frontiers in Medicine, vol.7, p.92.
[5] Amore A, Coppo R, Nedrud JG, et al. (2004). The role of nasal tolerance in a model of IgA nephropathy induced in mice by Sendai virus. Clin Immunol, vol.113, no.1, p.101-108.
[6] Yang Nannan, Wang, Jinquan. (2016). Abnormal intestinal mucosal immune function and IgA nephropathy. Journal of Nephrology and Dialysis Renal Transplantation vol.25, no.5, p.470-474.
[7] Gesualdo Loreto, Di Leo Vincenzo & Coppo Rosanna. (2021). The mucosal immune system and IgA nephropathy.. Seminars in immunopathology, vol.43, no.5, p.657-668.
[8] Qin Wei, Zhong Xiang, Fan Junming, et al. (2008). External suppression causes the low expression of the Cosmc gene in IgA nephropathy. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association, vol.23, no.5, p.1608-1614.
[9] Li Qiurong, Zhang Qiang, Wang Chenyan, et al. (2009). Altered distribution of tight junction proteins after intestinal ischaemia/reperfusion injury in rats. Journal of cellular and molecular medicine, vol.13, no.9B, p.4061-4076.
[10] Sui Weiguo, Xiao Min, Yang Ming, et al. (2017). Correlation of intestinal renal connection with IgA nephropathy. International Journal of Urology, vol.37, no.1, p.115-119.
[11] Tang Xiaoyang, Wu Gang. (2020). Progress of abnormal regulation of intestinal mucosal immunity in IgA nephropathy. Modern Medicine, vol.48, no.1, p.150-154.
[12] Coppo Rosanna. (2018). The gut-kidney axis in IgA nephropathy: role of microbiota and diet on genetic predisposition. Pediatric nephrology, vol.33, no.1, p.53-61.
[13] Zhao Mingming, Zhang Yu, Li Liusheng, et al. (2017). Mucosal immunity and treatment from pharynx in IgA nephropathy. Chinese Journal of Traditional Chinese Medicine Information, vol.24, no.7, p.15-18.
[14] Zhou Donghao, Xia Feifei, Liu Zhenchao, et al. (2019). An overview of the characteristics of the defensive action of Wei Qi in the Huangdi Neijing. Chinese Journal of Basic Chinese Medicine, vol.25, no.5, p.573-574+582.
[15] Xu Chaojin, Xi Xiaoxian, He Xinhuai. (2005). Identification of the correlation between Wei Qi and mucosal immunity. Journal of Traditional Chinese Medicine, no.1, p.120-123.
[16] Sun Jinyi, Sheng Meixiao. (2021). Advances in the understanding and treatment of IgA nephropathy in Chinese medicine based on mucosal immune mechanism. Journal of Zhejiang University of Traditional Chinese Medicine, vol.45, no.3, p.306-309+314.
[17] Zhao Jie, Meng Lifeng, Mo Chao, et al. (2020). Research progress in the prevention and treatment of IgA nephropathy based on the "pharyngeal and kidney-related" theory. World Science and Technology - Modernization of Chinese Medicine, vol.22, no.4, p.1148-1152.
[18] Bai Yawen, Ma Chunjie, Qian Zhanhong, et al. (2018). Study on the correlation between damp heat and mucosal immunodeficiency in IgA nephropathy. Chinese medicine information, vol.35, no.5, p.34-36.
[19] Shang Junfang, Liu Baohou, Wei Jinhui. (2015). Professor Liu Baohou's experience in identifying and treating kidney disease from damp-heat. Shi-Zhen Guomao Guomao, vol.26, no.10, p.2524-2525.
[20] Huang Saihua., Zheng Baolin, Yu Junwen, et al. (2007). Correlation between T cell subsets and TNF-α levels in IgA nephropathy in Chinese medicine. Capital Medicine, no.18, p.44-45.
[21] Zhan Yongli, Dai Xiwen. (2003). Clinical observation of 30 cases of chronic nephritis treated with the method of invigorating Qi and Blood, clearing heat and dampness. Journal of Traditional Chinese Medicine, no.12, p.922-924.
[22] Lu Fangfang. (2008). Zhou Zhongying's experience in treating nephritis from lung theory. Liaoning Journal of Traditional Chinese Medicine, no.10, p.1470-1471.
[23] Li Siping. (2015). Exploring the effect of "treatment from the pharynx" in the treatment of IgA nephropathy in Chinese medicine. Shenzhen Journal of Integrative Chinese and Western Medicine, vol.25, no.15, p.60-62.
[24] Wang Jiming. (2018). Clinical study on the treatment of IgA nephropathy from the pharynx in Chinese medicine. Chinese Journal of Integrated Chinese and Western Medicine and Nephrology, vol.19, no.1, p.74-75.
[25] Du Anmin. (2014). Clinical study on the treatment of IgA nephropathy by "treating from the pharynx" in Chinese medicine. Asia-Pacific Traditional Medicine, vol.10, no.8, p.69-70.
[26] Wang Xinhui, Liang Ying, Yu Renhuan, et al. (2019). Clinical study of Yiqi nourishing yin and sharpening pharynx formula combined with pharyngeal pecking treatment for IgA nephropathy with pharyngeal inflammation. Chinese Journal of Integrative Medicine, vol.39, no.1, p.52-56.
[27] Gao Hang, Zhao Yazhou, Liu Chunying. (2022). Understanding and treatment of IgA nephropathy in Chinese and Western medicine based on the intestinal-renal axis. Modern Chinese Medicine Clinics, vol.29, no.2, p.72-76.
[28] Chang Qintao, Bi Hongmei, Wang Ruihua, et al. (2017). Study of hs-CRP, IL-6 and IL-8 in patients with stage 4 chronic kidney disease by preserved enema with Yi kidney soup. Chinese Journal of Integrated Chinese and Western Medicine and Kidney Disease, vol.18, no.12, p.1068-1070.

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