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  4. Vol 3, Issue 6, 2022

Research Progress of Copper Metabolism and Disease Occurrence in Brain

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DOI: 10.23977/medsc.2022.030610 | Downloads: 9 | Views: 485

Author(s)

Jinyu Yao 1, Ziyu Zhao 1, Wenqing Wei 1, Jie Huang 2, Bao Xin 1

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Shihezi University, Shihezi, Xinjiang, 832099, China

Corresponding Author

Bao Xin

ABSTRACT

Copper is one of the indispensable metal elements in the human body. It participates in the regulation of metabolism and enzyme synthesis in the physical, and maintains the progress and evolution of the body and life activities. Especially in the nervous system, copper is also participated in myelination E, regulating synaptic plasticity activity likewise excitatory neuron Death and the signal cascade. The human brain is the controller of all life activities, so it is necessary to maintain the homeostasis of copper metabolism in the brain. Research shows that steady state copper metabolism disorders plays a crucial part in Alzheimer's disease (AD), Parkinson's disease (PD), and neurodegenerative diseases such as Wilson disease (WD). It is involved in the etiopathogenesis of many neurodegenerative diseases.Consequently, regulating this process is expected to furnish a fresh orientation for the study of the etiology of this disease. This article reviews the research progress on the correlation between the imbalance of copper metabolism homeostasis and the occurrence of diseases, so as to provide evidence for subsequent research.

KEYWORDS

Copper metabolism pathema, alzheimer's pathema, parkinson's pathema, wilson's pathema, neurodegenerative pathema

CITE THIS PAPER

Jinyu Yao, Ziyu Zhao, Wenqing Wei, Jie Huang, Bao Xin, Research Progress of Copper Metabolism and Disease Occurrence in Brain. MEDS Clinical Medicine (2022) Vol. 3: 57-61. DOI: http://dx.doi.org/10.23977/medsc.2022.030610.

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