Prevalence and Risk Factors of Hyperuricemia in Patients with Type 2 Diabetes Mellitus

Leilei Sun; Xiangsu Liu; Yue Wang

doi:10.23977/medsc.2022.030615

Prevalence and Risk Factors of Hyperuricemia in Patients with Type 2 Diabetes Mellitus

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DOI: 10.23977/medsc.2022.030615 | Downloads: 10 | Views: 472

Author(s)

Leilei Sun ¹, Xiangsu Liu ¹, Yue Wang ¹

Affiliation(s)

¹ Yanqing Hospital, Peking University Third Hospital, Yanqing, Peking, 102100, China

Corresponding Author

Leilei Sun

ABSTRACT

Objective: To investigate the prevalence and risk factors of hyperuricemia in patients with type 2 diabetes mellitus (T2DM). Methods: A total of 416 hospitalized patients with type 2 diabetes mellitus were divided into two groups according to whether they were complicated with hyperuricemia (HUA), type 2 diabetes mellitus group (T2DM with HUA, n=362) and type 2 diabetes mellitus with HUA group (T2DM with HUA, n=54). General demographic information was collected, present medical history and past medical history were inquired, and clinical biochemical indicators were detected. The prevalence of hyperuricemia in T2DM patients was analyzed. Pearson was used to analyze the correlation between hyperuricemia and other indicators. Binary Logistic regression was used to analyze the influencing factors of hyperuricemia in T2DM patients. Results: HUA54 cases were detected in 416 inpatients with type 2 diabetes mellitus, and the prevalence was 13. 0%. Logistic regression analysis showed that after adjusting for confounding factors, After adjusting for confounding factors, male, age, disease duration, BMI, TG, UREA, sCr and hypertension were risk factors for hyperuricemia in T2DM patients [OR(95%CI) were 1. 746 (1. 097-2. 348), 1. 06 (1. 022-1. 102), 1. 305 (1. 001-1. 605) and 1. 934, respectively] (1. 613-2. 305), 1. 865 (1. 104-2. 419), 6. 247 (2. 016-8. 943), 3. 547 (2. 092-6. 774), 4. 961 (2. 022-9. 618)]. Conclusion: Gender, age, disease duration, BMI, TG and hypertension are associated with hyperuricemia in T2DM patients, which can increase the risk of hyperuricemia in T2DM patients.

KEYWORDS

Type 2 Diabetes Mellitus, Hyperuricemia, Prevalence, Risk Factors For

CITE THIS PAPER

Leilei Sun, Xiangsu Liu, Yue Wang, Prevalence and Risk Factors of Hyperuricemia in Patients with Type 2 Diabetes Mellitus. MEDS Clinical Medicine (2022) Vol. 3: 87-95. DOI: http://dx.doi.org/10.23977/medsc.2022.030615.

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Prevalence and Risk Factors of Hyperuricemia in Patients with Type 2 Diabetes Mellitus

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