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  4. Vol 3, Issue 6, 2022

Research Advances in New Therapies for Thin Endometrium

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DOI: 10.23977/medsc.2022.030618 | Downloads: 20 | Views: 524

Author(s)

Ni Wang 1, Mei Chen 2, Yaqi Ai 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 710077, China

Corresponding Author

Mei Chen

ABSTRACT

Human assisted reproduction techniques are becoming increasingly sophisticated, but clinical observations suggest that patients with thin endometrium have poor clinical pregnancy outcomes. A variety of treatments have been reported in the literature, but the results remain unsatisfactory. New therapies include granulocyte colony-stimulating factor and regenerative medicine. Granulocyte colony-stimulating factor (G-CSF), a novel measure used in recent years to repair the endometrium and improve endometrial tolerance, was first reported in 2012 for the treatment of thin endometrium. Stem cells have the ability to infinitely self-renew and proliferate and differentiate into multiple cell types that can be targeted and induced into endometrial cells, and the current advantages of stem cell transplantation therapy are two fold: firstly, it can improve the endometrial thickness of thin endometrium, and secondly, it can improve endometrial tolerance, which has great promise and potential for application in the treatment of thin endometrium.

KEYWORDS

Thin Endometrium, Granulocyte Colony-Stimulating Factor, Regenerative Medicine

CITE THIS PAPER

Ni Wang, Mei Chen, Yaqi Ai, Research Advances in New Therapies for Thin Endometrium. MEDS Clinical Medicine (2022) Vol. 3: 107-112. DOI: http://dx.doi.org/10.23977/medsc.2022.030618.

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