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Advances in the Study of Adverse Reactions to Immune Checkpoint Inhibitors in Chinese and Western Medicine

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DOI: 10.23977/medsc.2022.030620 | Downloads: 8 | Views: 454

Author(s)

Yuyao Gao 1, Jianfeng Quan 2

Affiliation(s)

1 Shaannxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 710077, China

Corresponding Author

Jianfeng Quan

ABSTRACT

Lung cancer is currently the second most prevalent malignancy worldwide. The approval and clinical application of immune checkpoint inhibitors (ICIs) have led to a number of patients with non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) with varying degrees of disease Lung cancer has entered the era of immunotherapy with different degrees of benefit in progressionfree survival (PFS) and overall survival (OS). However, with the widespread clinical application of ICIS, several aspects of immune-related adverse events (irAEs) have emerged, posing a problem for the clinical application and exploration of ICIs. The use of Chinese medicine can significantly reduce the incidence of irAEs as well as alleviate the symptoms of adverse reactions, and also has a significant role in improving the quality of patient survival and prolonging patient survival.

KEYWORDS

Chinese Medicine, Immune Checkpoint Inhibitors, Immune-Related Adverse Reactions, Lung Cancer

CITE THIS PAPER

Yuyao Gao, Jianfeng Quan, Advances in the Study of Adverse Reactions to Immune Checkpoint Inhibitors in Chinese and Western Medicine. MEDS Clinical Medicine (2022) Vol. 3: 120-126. DOI: http://dx.doi.org/10.23977/medsc.2022.030620.

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