Research progress of Xuefu Zhuyu decoction in treating angina pectoris of coronary heart disease

Wang Yiming; Feng Lanshuan; Zhang Jie

doi:10.23977/medcm.2023.050306

Research progress of Xuefu Zhuyu decoction in treating angina pectoris of coronary heart disease

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DOI: 10.23977/medcm.2023.050306 | Downloads: 10 | Views: 430

Author(s)

Wang Yiming ¹, Feng Lanshuan ¹, Zhang Jie ²

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, 712046, China
² Department of Cardiology, Xi'an Fifth Hospital, Xi'an, Shaanxi, 710000, China

Corresponding Author

Wang Yiming

ABSTRACT

Coronary atherosclerotic heart disease (CHD) is one of the common chronic diseases. The clinical incidence of CHD angina pectoris (AP) is extremely high, and the mortality rate is also rising all year round. Xuefu Zhuyu Decoction (XZD) first appeared in "Yilin Gaicuo". It is a famous prescription for treating blood stasis syndrome. Current mechanism studies have shown that XZD can treat AP through multiple targets and multiple pathways, and can also reduce myocardial and arterial damage by interfering with CRP, hs-CRP, TNF-α, and IL-6 inflammatory mediators, and can also affect platelet-activating factor (PAF) to relieve inflammation. Coronary sclerosis and thrombosis etc. Clinical trials have shown that XZD treatment of AP patients can reduce the number of AP attacks, shorten the duration of AP, improve ECG performance, improve hemorheology indicators, improve TCM syndrome scores, reduce the levels of TC, TG, LDL-C and other indicators, and reduce adverse reactions Compared with conventional western medicine, it has fewer side effects and higher safety. This article summarizes relevant literature on XZD treatment of AP in recent years by CNKI, Wanfang, VIP, etc., and reviews its mechanism and clinical research, in order to provide reference for clinical XZD treatment and research on AP.

KEYWORDS

Xuefu Zhuyu Decoction (XZD); coronary atherosclerotic heart disease (CHD); angina pectoris (AP); mechanism of action; clinical research

CITE THIS PAPER

Wang Yiming, Feng Lanshuan, Zhang Jie, Research progress of Xuefu Zhuyu decoction in treating angina pectoris of coronary heart disease. MEDS Chinese Medicine (2023) Vol. 5: 46-52. DOI: http://dx.doi.org/10.23977/medcm.2023.050306.

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Research progress of Xuefu Zhuyu decoction in treating angina pectoris of coronary heart disease

Author(s)

Affiliation(s)

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ABSTRACT

KEYWORDS

CITE THIS PAPER

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