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Correlation between Parkinson's Disease and Glutamate Metabolism

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DOI: 10.23977/phpm.2023.030103 | Downloads: 5 | Views: 418

Author(s)

Yuxia Zhang 1, Qiong Liang 2, Dingguo Li 3, Yuanzhu Li 1, Mingzhu Pan 1, Yanan Zou 1

Affiliation(s)

1 School of Health, Hainan Technology and Business College, Haikou, Hainan, 570203, China
2 Hainan Provincial Institute for Food and Drug Control Haikou Branch, Haikou, Hainan, 570311, China
3 School of Basic Medicine and Life Sciences, Hainan Medical College, Haikou, Hainan, 571199, China

Corresponding Author

Yanan Zou

ABSTRACT

Parkinson's disease is a degenerative disease of the nervous system, which mainly occurs in middle-aged and elderly people. With the deepening of disease research, it is found that there is a close relationship between the emergence of the disease and the pathological changes of the "substantia nigra" cells in the brain, leading to decreased dopamine synthesis, inhibition of the function of acetylcholine, increased acetylcholine excitability, and paralysis. In recent years, studies have found that abnormal glutamate metabolism is also an important factor affecting Parkinson's disease, which plays an important role in the treatment of the disease. Therefore, studies on the correlation between Parkinson's disease and glutamate metabolism will provide better conditions for comprehensive understanding and treatment of the disease.

KEYWORDS

Parkinson's Disease; Glutamic Acid; Metabolism; Relevance

CITE THIS PAPER

Yuxia Zhang, Qiong Liang, Dingguo Li, Yuanzhu Li, Mingzhu Pan, Yanan Zou, Correlation between Parkinson's Disease and Glutamate Metabolism. MEDS Public Health and Preventive Medicine (2023) Vol. 3: 17-21. DOI: http://dx.doi.org/10.23977/phpm.2023.030103.

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