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Prevention Effects of Spices on Hyperglycemia and Diabetes Mellitus

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DOI: 10.23977/medsc.2023.040306 | Downloads: 17 | Views: 467

Author(s)

Liyuan Fang 1, Hongyan Zhang 2, Tao Feng 2, Linyu Ma 2

Affiliation(s)

1 Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe, 657-8501, Japan
2 Yunnan Institute of Medical Device Testing, Kunming, China

Corresponding Author

Liyuan Fang

ABSTRACT

Diabetes mellitus is one of the human health problems since it causes multiple complications. The presence of hyperglycemia is one of the key signs of diabetes. According to recent research, spice extracts and their active compounds have a wide range of pharmacological actions, including anti-inflammation and anti-hyperglycemia properties. They can significantly reduce the effects of diabetes and alleviate its symptoms in a sea of ways. Clinical investigations have demonstrated that spice extracts and their active ingredients are effective in treating insulin resistance and problems of lipid metabolism. This review surveys and presents information about the active ingredients, traditional uses and antidiabetic effects of aromatic spices. As well as the potential pharmacological properties of aromatic spices and extracts.

KEYWORDS

Spices, Diabetes mellitus, Active compounds, Glucose uptake

CITE THIS PAPER

Liyuan Fang, Hongyan Zhang, Tao Feng, Linyu Ma, Prevention Effects of Spices on Hyperglycemia and Diabetes Mellitus. MEDS Clinical Medicine (2023) Vol. 4: 46-52. DOI: http://dx.doi.org/10.23977/medsc.2023.040306.

REFERENCES

[1] Lim Soo, et al. "COVID-19 and diabetes mellitus: from pathophysiology to clinical management." Nature Reviews Endocrinology 17.1 (2021): 11-30.
[2] Shang A, Cao S Y, Xu X Y, et al. Bioactive compounds and biological functions of garlic (Allium sativum L.) [ J]. Foods, 2019, 8(7): 246.
[3] Nigil Haroon N, Anton A, John J, et al. Effect of vitamin D supplementation on glycemic control in patients with type 2 diabetes: a systematic review of interventional studies. Journal of Diabetes & Metabolic Disorders, 2015, 14(1): 1-11.
[4] Kuo J J, Chang H H, Tsai T H, et al. Curcumin ameliorates mitochondrial dysfunction associated with inhibition of gluconeogenesis in free fatty acid-mediated hepatic lipoapoptosis. International journal of molecular medicine, 2012, 30(3): 643-649.
[5] Couturier K, Qin B, Batandier C, et al. Cinnamon increases liver glycogen in an animal model of insulin resistance [J]. Metabolism, 2011, 60(11): 1590-1597.
[6] LU Z L. Hypoglycemic activity of cinnamon polyphenol and its mechanism. Shanghai: Second Military Medical University, 2011.
[7] Oboh G, Akinbola I A, Ademosun A O, et al. Essential oil from clove bud (Eugenia aromatica Kuntze) inhibit key enzymes relevant to the management of type-2 diabetes and some pro-oxidant induced lipid peroxidation in rats pancreas in vitro. Journal of oleo science, 2015: ess14274.
[8] Watcharachaisoponsiri T, Sornchan P, Charoenkiatkul S, et al. The α-glucosidase and α-amylase inhibitory activity from different chili pepper extracts. International Food Research Journal, 2016, 23(4).
[9] Derosa G, Maffioli P. Α-Glucosidase inhibitors and their use in clinical practice. Arch Med Sci, 2012, 8(5): 899-906.
[10] Soliman M M, Ahmed M M, El-Shazly S A. Cinnamon extract regulates gene expression of lipid and carbohydrate metabolism in streptozotocin induced diabetic wistar rats. Am J Biochem Biotechnol, 2013, 9(2): 172-182.
[11] Hester F, Verghese M, Willis S, et al. The Anti-Diabetic Potential of Thermally Treated Garlic, Turmeric, and Ginger in Pre-Diabetic Male Wistar Rat Model. Food and Nutrition Sciences, 2018, 9(04): 420.
[12] Quirarte-Báez S M, Zamora-Perez A L, Reyes-Estrada C A, et al. A shortened treatment with rosemary tea (rosmarinus officinalis) instead of glucose in patients with diabetes mellitus type 2 (TSD). Journal of Population Therapeutics and Clinical Pharmacology, 2019, 26(4): e18-e28.
[13] Tian L, Jin T. The incretin hormone GLP‐1 and mechanisms underlying its secretion: The incretin hormone GLP-1 and mechanisms underlying its secretion. Journal of diabetes, 2016, 8(6): 753-765.
[14] Haldar, Sumanto, Siok C C, et al. "Polyphenol-rich curry made with mixed spices and vegetables increases postprandial plasma GLP-1 concentration in a dose-dependent manner." European journal of clinical nutrition 72.2 (2018): 297-300.
[15] Masaki, et al. "Curcumin improves glucose tolerance via stimulation of glucagon-like peptide-1 secretion." Molecular Nutrition & Food Research (2016).
[16] Akash, Muhammad, Kanwal, et al. "Spice plant Allium cepa: Dietary supplement for treatment of type 2 diabetes mellitus." Nutrition 30.10 (2014): 1128-1137.
[17] Ranilla, Lena Galvez, et al. "Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America." Bioresource technology 101.12 (2010): 4676-4689.
[18] Adegbola, Ifeoluwa, et al. "Combined ginger and garlic extract improves serum lipid profile, oxidative stress markers and reduced IL-6 in diet induced obese rats." Obesity Medicine 23 (2021): 100336.
[19] Habtemariam s. Preface [M]//Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases. Amsterdam: Elsevier, 2019: xv-xviii.
[20] Mirmosayyeb, Omid, et al. "Possible role of common spices as a preventive and therapeutic agent for Alzheimer's disease." International journal of preventive medicine 8 (2017).
[21] Frydman-Marom A, Levin A, Farfara D, et al. Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer’s disease animal models[J]. PLoS One, 2011, 6(1): e16564. 

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