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  4. Vol 4, Issue 3, 2023

Safety of Open Surgery and Total Endoscopic Anastomosis Assisted Radical Resection of Colorectal Cancer (CRC)

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DOI: 10.23977/medsc.2023.040310 | Downloads: 17 | Views: 678

Author(s)

Sakarie Mustafe Hidig 1, Haotian Li 1, Xiaocheng Zhu 2, Yong Shao 2

Affiliation(s)

1 Department of Gastrointestinal Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu, China
2 Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, Jiangsu, China

Corresponding Author

Sakarie Mustafe Hidig

ABSTRACT

To study the safety of open surgery and total endoscopic anastomosis assisted radical resection of colorectal cancer. 100 patients with rectal cancer admitted to our hospital from March 2020 to May 2022 were selected as the subjects of this study. According to the operation method, the patients were randomly assigned into two groups, namely the control group and the observation group, with 50 cases each. The control group was treated with open rectal resection. After understanding the surgical treatment plan, the patients could be anesthetized, and lithotomy position was taken. The operation started from the middle of the abdomen, the mesentery was opened in the abdomen, the corresponding intestinal segment was isolated from the colonic artery, and the blood vessels on it were ligation with the surrounding lymph nodes. The intestinal tube was cut off at the position 5 cm away from the tumor, and then the small intestine was anastomosed, and then the distilled liquid was used to clean the bleeding carefully. After the hemostasis was completed, the drainage tube was inserted, and the wound was sutured. Observation group was treated with open surgery and total endoscopic anastomosis assisted radical resection of colorectal cancer. By comparing the operation conditions of the two groups, the intraoperative blood loss in the observation group is significantly lower than that in the control group, and the operation time and postoperative hospital stay are significantly lower than that in the control group. By analyzing the serum levels of IL-6, CRP and TNF-α in the two groups, the levels of IL-6, CRP and TNF-α were higher in both groups after surgery than before surgery. The levels of IL-6, CRP and TNF-α in the observation group were significantly lower than those in the control group. Through the analysis of serum motilin and gastrin levels in the two groups, the levels of motilin and gastrin in the two groups 3 days after surgery were lower than before surgery, and the levels of motilin and gastrin in the observation group were higher than those in the control group. Through observation, the number of postoperative incision infection cases in the control group was 4 cases, anastomotic bleeding cases were 3 cases, and intestinal obstruction cases were 5 cases. The concurrent probability was 24.00% (12/50). In the observation group, there were 2 cases of postoperative incision infection, 1 case of anastomotic hemorrhage and 1 case of intestinal obstruction, and the complication probability was 8.00% (4/50). The probability of complications in the observation group was significantly lower than that in the control group, and the analysis difference between the two groups was statistically significant (P < 0.05). The therapeutic effect of open surgery and total endoscopic anastomosis assisted radical resection of colorectal cancer is significantly better than that of traditional open surgery, which is worthy of promotion in clinical treatment.

KEYWORDS

Open Surgery, Full Cavity Mirror, Rectal Cancer, Total Endoscopic Anastomosis

CITE THIS PAPER

Sakarie Mustafe Hidig, Haotian Li, Xiaocheng Zhu, Yong Shao, Safety of Open Surgery and Total Endoscopic Anastomosis Assisted Radical Resection of Colorectal Cancer (CRC). MEDS Clinical Medicine (2023) Vol. 4: 78-85. DOI: http://dx.doi.org/10.23977/medsc.2023.040310.

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