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  4. Vol 4, Issue 1, 2023

Progress of ferroptosis in gastrointestinal tumors

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DOI: 10.23977/tranc.2023.040108 | Downloads: 14 | Views: 403

Author(s)

Zhang Chanchan 1, Sun Jianfei 2, Guo Hui 2, Si Mingming 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China
2 The First Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China

Corresponding Author

Sun Jianfei

ABSTRACT

Ferroptosis is a new method of programmed cell death, which is different from other cell death. It is characterized by cytoplasmic membrane blistering, chromatin condensation, mitochondrial shrinkage, volume reduction, membrane density increase, cristae reduction or disappearance, mitochondrial outer membrane rupture, and nuclear membrane integrity. It plays an important role in the treatment of tumors, especially in gastrointestinal tumors, and has potential research potential. This article will review the mechanism of ferroptosis and its related reports on gastrointestinal tumors in recent years.

KEYWORDS

Ferroptosis, gastric cancer, colorectal cancer

CITE THIS PAPER

Zhang Chanchan, Sun Jianfei, Guo Hui, Si Mingming, Progress of ferroptosis in gastrointestinal tumors. Transactions on Cancer (2023) Vol. 4: 54-59. DOI: http://dx.doi.org/10.23977/tranc.2023.040108.

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