Education, Science, Technology, Innovation and Life
Open Access
Sign In

Effect of Petroleum Ether Extract from Rhizoma Amorphophalli (SLG) on Proliferation and Apoptosis of Non-small Cell Lung Cancer A549 Cells

Download as PDF

DOI: 10.23977/medsc.2023.040706 | Downloads: 8 | Views: 360

Author(s)

Wang Kai 1,2, Wang Junhui 2, Yang Huiling 3, Mang Gongxian 2, Xiao Meng 2

Affiliation(s)

1 Xi'an Chang'an District Hospital of Shaanxi Province, Xi'an, 710100, China
2 Shaanxi University of Chinese Medicine, Xianyang, 712046, China
3 Xi'an Jiaotong University First Affiliated Hospital, Xi'an, 710061, China

Corresponding Author

Wang Kai

ABSTRACT

Lung cancer has become one of the cancers that seriously threaten human life, with the highest morbidity and mortality in all countries of the world. At present, the treatment of lung cancer is mainly based on surgery, adjuvant chemotherapy and radiotherapy, but these treatments have adverse consequences for the prognosis and quality of life of patients with lung cancer. With the development of traditional Chinese medicine technology, traditional Chinese medicine and traditional Chinese medicine compound have achieved good clinical efficacy in the treatment of lung cancer. The traditional Chinese medicine Sheliugu has the effect of clearing heat and detoxifying, dispersing and detumescence, and the clinical curative effect is remarkable. In this paper, lung cancer A549 cells were used as the research object to explore the effect of petroleum ether extract of traditional Chinese medicine Heliugu on the proliferation and apoptosis of lung cancer A549 cells.

KEYWORDS

Petroleum ether extract of Amorphophallus; lung cancer A549 cells; cell proliferation; apoptosis

CITE THIS PAPER

Wang Kai, Wang Junhui, Yang Huiling, Mang Gongxian, Xiao Meng, Effect of Petroleum Ether Extract from Rhizoma Amorphophalli (SLG) on Proliferation and Apoptosis of Non-small Cell Lung Cancer A549 Cells. MEDS Clinical Medicine (2023) Vol. 4: 30-35. DOI: http://dx.doi.org/10.23977/medsc.2023.040706.

REFERENCES

[1] Xu Jing, Yu Xin, Ma Hongtao, et al. Trend analysis of lung cancer death in China from 2006 to 2020 based on age-period-cohort model [J]. Tumor prevention and treatment research, 2023, 50 (8): 788-793. 
[2] Broderick SR. Adjuvant and Neoadjuvant Immunotherapy in Non-small Cell Lung Cancer [J]. Thorac Surg Clin. 2020; 2: 215-220. 
[3] Pan Lei, Fang Meiling, Chen Peifeng. Experimental study on the apoptosis of human gastric cancer SGC-7901 cells induced by petroleum ether extract of traditional Chinese medicine Heliugu [J]. Chinese Journal of Traditional Chinese Medicine, 2012, 30 (6): 1259-1261. 
[4] Zhen Yan. Study on the anti-tumor efficacy of petroleum ether extract of Amorphophallus hexandra [J]. Chinese Medicine and Clinical, 2019, 19 (1): 151-152. 
[5] Cheng Quan, Fu Huazhou. Research progress on adjuvant treatment of non-small cell lung cancer with traditional Chinese medicine compound [J]. Journal of Liaoning University of Traditional Chinese Medicine, 2016, 18, (1):141-143. 
[6] Zou Wenyuan, Ge Xin, Fan Xiaoqiu, etc. Clinical application and mechanism of action of Sheliugu anti-tumor [J]. World Traditional Chinese Medicine, 2019, 14 (7): 1911-1914. 
[7] Xu Fei, Li Xuejun, Zhang Qiangqiang. The application of traditional Chinese medicine Sheliugu in the treatment of pancreatic cancer [J]. Journal of Shaanxi University of Traditional Chinese Medicine, 2022, 45 (1):132-136. 
[8] Chang Zhongfei, Chen Peifeng, Wu Qiaofeng, etc. Seliugu petroleum ether extract column chromatography site to see the tumor active component screening again [J]. Journal of Zhejiang University of Traditional Chinese Medicine, 2011, 35 (5):753-755. 
[9] Yu Xiaoling, Zhao Yanna, Yin Liming, et al. The effect and mechanism of petroleum ether extract from Agkistrodon acutus on the biological characteristics of K562 cells [J]. Chinese Journal of Experimental Hematology, 2021, 29 (4):1028-1033. 
[10] Lv Xiaoai. Experimental study on the inhibition of recurrence and metastasis of triple-negative breast cancer by intervention of PI3K / Akt signaling pathway [D]. Zhejiang University of Traditional Chinese Medicine, 2013. 
[11] Cai Yong, Li Xiaoping. Jianpi Liqi Chinese medicine combined with interventional treatment of breast cancer liver metastasis in 40 cases [J]. Shaanxi Traditional Chinese Medicine, 2005, 26(6):491-493. 
[12] Xu Fei, Li Xuejun, Liu Yanfeng, etc. Application of Sheliugu in the treatment of lung cancer [J]. Journal of Hubei University of Traditional Chinese Medicine, 2021, 23(5):119-121.

Downloads: 4549
Visits: 196893

Sponsors, Associates, and Links


All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.