Author(s)

Lei Zhang, Xinhua Cheng

Corresponding Author

Xinhua Cheng

ABSTRACT

Objective: to discuss the effect of local injection of platelet rich plasma on repair of rats’ ruptured achilles tendon tissue. Method: 80 rats with ruptured achilles tendon were chosen in this study, and they were classified into two groups with double blind method. The control group (40 rats) was not treated, while platelet rich plasma was locally injected for the observation group (40 rats). The repair of ruptured achilles tendon tissue in both groups was compared and analyzed. Results: the grading of tendon adhesion degree in both groups presented exacerbation 1-4w after the treatment, P＞0.05. At the rupture of achilles tendon of rats in the observation group, the improvement degree of positive density value of collagenous fiber I was superior to the control group. In the biomechanics test, the elasticity modulus and maximum tensile strength were superior to the control group, P＜0.05. The maximum sliding distance of both groups had no difference, P＞0.05. Conclusion: local injection of platelet rich plasma for the rats after the rupture of achilles tendon has the obvious effect, and it can accelerate achilles tendon tissue healing.

KEYWORDS

Rat, rupture of achilles tendon, platelet rich plasma, tissue repair