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Study on the Clinical Manifestations and Diagnostic Criteria of Premature Ovarian Failure

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DOI: 10.23977/medeb.2018.07015


Lili Xuan, Xiaojun Liu

Corresponding Author

Xiaojun Liu


Premature ovarian failure (POF) refers to a disease characterized by amenorrhea, infertility, estrogen deficiency, and elevated gonadotropin levels in women before 40-year-old. This paper reports that the incidence of premature ovarian failure is 1% before 40 and 1 before 30. The prevalence of POF in primary amenorrhea patients is 10% to 28%, and the POF incidence in secondary amenorrhea is 4 % ~ 18%. This paper briefly discusses its clinical manifestations and diagnostic criteria.


Clinical manifestations, diagnostic criteria, premature ovarian failure

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