Author(s)

Gu Yinglin, Cheng Yuexin

Corresponding Author

Gu Yinglin

ABSTRACT

Objective: To optimize and improve Cang’erzi rhinitis capsule that under multi-standard parallel quality specification. Methods: Using TLC to legally identify prescriptions that including Radix Angelicae Dahuricae, Flos Magnoliae and Fructus Xanthii Using the high performance liquid chromatography to measure the baicalin’s content in Xanthium rhinitis capsules. Results: Radix Angelicae Dahuricae, Flos Magnoliae and Fructus Xanthii could be detected by TLC,and the spots were clear, specific and negative control no interference; The correlation coefficient 0.083 μ g ~ 0.834 μ g was r ≥ 0.999.The average recovery was 98.5% and RSD (the relative standard deviation) was 0.9%. Conclusion: The research data show that the amount of baicalin in the samples of three different manufacturers is obviously different, and it is necessary and feasible to unify the national standard, which is more beneficial to control the quality of Xanthium sibiricum rhinitis capsule.

KEYWORDS

Xanthium rhinitis capsule, Thin layer chromatography, High performance liquid chromatography, Multi-standard parallelism