Author(s)

Ke Chen

Corresponding Author

Ke Chen

ABSTRACT

Cancer has always been the leading cause of death, with high mortality rate and low curability. Meanwhile, the incidence rate of various types of cancer is growing with time. Cytokine is a substance that regulate the activity of various immune cells. The usage of various cytokines to treat cancer had been studied in some research groups. This paper mainly attended to the history, mechanisms, and the effects of interleukin-2(IL-2) and interferon-alpha on various cancers as mono therapy or adjuvant therapy. This review further discussed the potential drawbacks, the development bottlenecks, and the future prospect of cytokine in immunotherapy.

KEYWORDS

Cytoline, immunotherapy, cancer