Author(s)

Baixi He, Chenfei Lv, Jingru Zhang

Corresponding Author

Baixi He

ABSTRACT

From the public health perspective, the trend of cancer prevalence increased significantly every year, which is a sufficient reason for immunotherapy emergence and application. CAR T-cell is one of the emerging immunotherapies which have already made several effective achievements at this stage. This article aims to mainly illustrate the application of CAR T-cell therapy. In this article, five FDA-approved CAR T-cell therapies also some related information will be introduced. Based on the research, the consequences of these treatments all showed effectiveness to their target cancer based on the overall response rate, complete response rate, and duration of response evaluation.

KEYWORDS

CAR T therapy, adoptive cellular immunotherapy, cancer