Author(s)

Wenmin Si

Corresponding Author

Wenmin Si

ABSTRACT

Coronavirus (COVIDS-19,SARS-CoV-2) is an acute respiratory infectious disease caused by the 2019 coronavirus infection and broke out in Hubei It is the most widespread global pandemic to hit humans in the last hundred years. It is an infectious disease caused by mammals and birds and can spread rapidly through direct, aerosol and contact transmission and is subject to early mutation. It has been shown in numerous scientific studies to be pandemic in nature, and its spread and severity is of great concern, its performance was significantly better than the spatial extent of the Middle East Respiratory Syndrome and SARS disaster areas and the number of people affected. It was targeting middle-aged and elderly people in their 50s and accompanying, in most individuals, expressions of dry cough, weariness, and fever. The early identification, research and dissemination of knowledge about this virus is of great importance to society and can effectively prevent the spread of the virus. This virus is a major threat to society, and its pathogenesis and interventions are becoming increasingly important and have become a hot topic in academia. This paper will therefore review and discuss the basic scientific mechanisms of SARS-Cov-2, including genetic quality, receptor restriction, expected zoonosis, and the research and evolution of interventions and pharmacological mechanisms that can be implemented, in addition to providing an outlook on future research trends.

KEYWORDS

Coronavirus, pathological model, intervention, treatment