Author(s)

Fan Zhang

Corresponding Author

Fan Zhang

ABSTRACT

At present, the global epidemic of COVID-19 situation continues to be serious. Vaccines are an important step in controlling the COVID-19 pandemic, but as vaccinations move forward, there are challenges. First of all, the article mainly introduces the basic situation of several major new virus variants that appear with the continuous development of the epidemic and whether existing vaccines remain effective against these variants. Specific examples and characteristic analyses are made for the two main types of variants, variant of interest and variant of concern. Second, it explores whether vaccines should be used in some special populations or whether other negative effects will emerge. The impact of the vaccine on these people is still unclear, and these people do not recommend vaccination at present. Then, the side effects of the vaccine are listed in more detail. In addition, Take the research surveys in the United States and China as examples to analyze different people's attitudes towards vaccination and the trend that more and more people are willing to vaccinate. Finally, to improve the ability of future vaccination to control the epidemic situation and the effectiveness of vaccines to the diverse variants, some suggestions for the next generation vaccine were put forward.

KEYWORDS

COVID-19, vaccination, variants, side effects, next-generation vaccines