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Mesenchymal stem cell-derived exosomes therapy: research progress and mechanism of action

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DOI: 10.23977/behdp.2021001

Author(s)

Sicheng Pan

Corresponding Author

Sicheng Pan

ABSTRACT

Stem cell-derived exosomes are an important component of stem cell research and are getting more and more attention. Mesenchymal stem cell-derived exosomes are one of the main sources of stem cell-derived exosomes. However, there is still a long way to go before mesenchymal stem cell-derived exosomes therapy can be used clinically, and it needs a better understanding of the specific cell sources, mechanisms of disease treatment, target spot. It is essential to keep abreast of the latest developments in this rapidly evolving field and know which sources can be used and which ways can be treated which diseases. This article summarizes current and developing mesenchymal stem cell-derived exosomes therapies for treating diseases such as a tumor, neurodegenerative diseases, allergic diseases, wound healing, renal injury, and liver diseases; and provides some necessary guidance for future exosome applications.

KEYWORDS

Mesenchymal stem cell (MSCs), Exosomes, Mesenchymal stem cell-derived exosomes, Therapeutics

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