Author(s)

Junzhe Chen, Yun Li and Zijian Pang

Corresponding Author

Junzhe Chen

ABSTRACT

α-neurotoxin is a toxin isolated from most of snake poison. Scientists have developed methods to neutralize the toxin and to treat the poisoning patients. Studies have found a series of peptide which make it easier to combine with α-neurotoxin. Thus, in this way, α-neurotoxin would not be available to combine with nACHR where it causes the disease. This review discusses how the researchers have design and synthesis the peptide through focusing on the sample that have a high affinity of α-neurotoxins and replacing amino acids to receive a better affinity. Moreover, the library researchers have built to further study of peptides in treatment or other potential purposes are also discussed.

KEYWORDS

α-neurotoxin, poison, high affinity peptides, peptide library