Author(s)

Jiachen Ai

Corresponding Author

Jiachen Ai

ABSTRACT

Infertility has become a common medical concern and a global public health issue in recent decades. Lifestyles may be incrementally altering epigenome, according to accumulating evidence. In the recent decade, for the mass and variety of the database and the desire for a general view of data to draw wildly applicable conclusions, biostatistical research methods combining developed arithmetic models are widely used in finding factors influencing semen quality. This paper looks back at previous scholarships that used biostatistics research methods to determine the relationship between sperm quality and certain lifestyles. Factors reviewed include dietary habits, body mass index (BMI), stress, consumption of alcohol and smoking, mobile phone use, and microplastics. Convincing conclusions are thus drawn. Food molecules or those decomposed after cooking can alter metabolic pathways by altering the epigenome, resulting in changes in fertility. Besides, obesity and regular alcohol consumption are linked to lower semen quality and alterations in reproductive hormones, like testosterone and sex hormone-binding globulin, suggesting intersections in pathways. Those taken for granted and with less attention/legislations applied in modern life, like mobile phone usage and overused plastics, in turn, become potential threats to public health. Meta-analysis has been most utilized to address issues under the current topic in the reviewed literature. Among all factors, age is an inevitable and constant factor impacting sperm parameters; Thus, it should be considered as a confounder and limited.

KEYWORDS

Semen quality, Biostatistics, Dietary Habits, BMI