Is ion-channel a novel target for neuron disorder? Through study from mechanism to perspective
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DOI: 10.23977/blsme.2022007
Corresponding Author
Yiwen Yang
ABSTRACT
Through experiments, understanding the role of ion channels in the central nervous system and making ion channels become targeted therapies for central nervous system diseases from an electrophysiological perspective are potential topics in the future. There is still no effective systematic treatment for a large number of neurological diseases, so it is essential to find a new breakthrough for them. Through reading a large number of research papers and experimental reports, three of the most prevalent neurological diseases are selected to analyze their pathogenesis and mechanism, as well as how mutated ion channels cause them. These three diseases include Alzheimer's disease, multiple sclerosis, and epilepsy. A number of papers and reports show that when ion channels are mutated, different variations can cause different levels of damage to our health. Therefore, this paper calls on scientists to explore more ion channel targeted therapies for neurological diseases and figure out the unsolved mechanisms and causes of neurological diseases.
KEYWORDS
Ion channel, Alzheimer’s disease, Multiple Sclerosis, Epilepsy, voltage-gated ion channel