Author(s)

Yunman Gu, Yingying He and Yutong Li

Corresponding Author

Yunman Gu

ABSTRACT

The outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 [COVID-19]) has led to the unprecedented public health crisis. With the rapid spread, the hospitalization and death rate were surge worldwide. In response to the COVID-19 pandemic, several vaccine candidates were developed to control the spreading. The mechanism, advantages, and disadvantages of vaccines techniques used in the production of vaccines against COVID-19, including inactivated, nucleic acid-based, adenovirus, and subunit approaches, were discussed. Currently, vaccine candidates based on various platforms have entered phase III trials and have been widely used in many countries. Moreover, there are medications used to eliminate the severe respiratory symptoms of COVID-19, including Remdesivir and Monoclonal Antibodies. However, with the emergence of new variants of COVID-19, such as Delta variants, there is a need for the ongoing development of vaccines and medications to overcome the potential new outbreak of COVID-19 in the future.

KEYWORDS

COVID-19, Vaccine, Drugs, Latest Advances, Inactivated Vaccine, Adenovirus Vaccine, Remdesivir