Author(s)

Tongzhou Li

Corresponding Author

Tongzhou Li

ABSTRACT

The efficacy of many of the active components of tea polyphenols has been demonstrated, with the active ingredient epigallocatechin gallate (EGCG) appearing in many human health-related experiments. This article collects the latest research demonstrating the relevance of EGCG and its derivatives to human health. Inhibition of cancer cell proliferation, combination with other active substances, and use of nanoparticles as carriers are the main mechanisms by which EGCG fights tumor cells; different concentrations of EGCG have antioxidant properties with different potencies, and β-lacto globulin is modified by EGCG to have a stronger antioxidant potential. Enzyme-enhanced catechins showed stronger anti-aging activity, and theanine ameliorated the shortened lifespan induced by high doses of EGCG. EGCG resists the development of neurodegenerative diseases by inhibiting changes in the action of proteins. This paper describes the use of EGCG and its derivatives for health promotion and provides a direction for future clinical applications of EGCG.

KEYWORDS

EGCG, Anti-cancer, Antioxidant, Anti-aging, Neuroprotective, Bioactivity