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Effect of Decoction for Clearing Liver and Removing Dampness Activating Blood Circulation on the Efficacy and Liver Function Indicators of Non-Alcoholic Fatty Liver Disease

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DOI: 10.23977/medcm.2024.060101 | Downloads: 9 | Views: 246

Author(s)

Guoxiang Liu 1, Zhichao Wang 2, Xiaohui Zhang 3, Sreemoy Kanti Das 1

Affiliation(s)

1 Faculty of Pharmacy, Lincoln University College, Petaling Jaya, Selangor, Malaysia
2 Department of Medicine, Lincoln University College, Petaling Jaya, Selangor, Malaysia
3 Department of Rehabilitation Medicine, Heilongjiang Nursing College, Harbin, Heilongjiang, China

Corresponding Author

Sreemoy Kanti Das

ABSTRACT

Traditional studies have not covered the comprehensive study of decoction for clearing liver and removing dampness activating blood circulation (CLRDA) on non-alcoholic fatty liver, lacking standard treatment or comparison between placebo group and decoction for CLRDA, which challenges the credibility of the conclusions. This study used the "decoction for CLRDA" formula to treat non-alcoholic fatty liver disease (NAFLD), using a randomized controlled trial. This article divides patients into multiple groups, with the treatment group receiving a specific combination of traditional Chinese medicine (TCM), and the control group receiving other TCM treatments. During the treatment period, regular follow-up monitoring is conducted, and this article records patient demographics, clinical symptoms, and liver function indicators. The data analysis uses t-value test and p-value test to compare the differences between two groups, ensuring the reliability of the results. During the treatment process, the "decoction for CLRDA" group achieved significant success in liver function indicators. Specific data showed that after treatment, the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were significantly reduced. The t-value is -7.83 and the p-value is 0.014, indicating a statistically significant difference compared to the control group. This strongly supports the efficacy of "decoction for CLRDA" in treating NAFLD.

KEYWORDS

Decoction for CLRDA, Non-Alcoholic Fatty Liver, Randomized Controlled Trial, AST and ALT

CITE THIS PAPER

Guoxiang Liu, Zhichao Wang, Xiaohui Zhang, Sreemoy Kanti Das, Effect of Decoction for Clearing Liver and Removing Dampness Activating Blood Circulation on the Efficacy and Liver Function Indicators of Non-Alcoholic Fatty Liver Disease. MEDS Chinese Medicine (2024) Vol. 6: 1-8. DOI: http://dx.doi.org/10.23977/medcm.2024.060101.

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