Author(s)

Zhengfang Zhou ¹, Panpan He ¹, Peng Lei ²

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, 712046, China
² Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, China

Corresponding Author

Peng Lei

ABSTRACT

Xuefu Zhuyu Decoction is a classic prescription, which is mainly used for the treatment of chest blood stasis. In recent years, with the in-depth study of this formula and related drugs, it is found that it is widely used in the prevention and treatment of cardiovascular diseases such as coronary heart disease, angina pectoris, arrhythmia, chronic heart failure and restenosis after interventional treatment. Through the literature search, this paper combs, analyzes and summarizes the three aspects of prescription, pharmacology and clinical treatment of the decoction, aiming to provide more thinking directions for its clinical application. Xuefu Zhuyu Decoction has a long history and precise therapeutic effect [1]. In the prescription,Peach kernel, Radix Paeoniae Rubra , safflower and hyssop can promote menstruation, relieve pain, activate Blood circulation and remove Blood stasis; Angelica sinensis and Rhizoma Ligustici Chuanxiong can promote Yang and disperse knots, activate Blood circulation and nourish Blood; Hovenia dulcis can relieve depression and dredge the Liver.Modern pharmacology has confirmed that Xuefu Zhuyu Decoction can promote neovascularization, reduce blood lipid levels, inhibit inflammatory reactions, inhibit vascular remodeling, anti-fibrosis, and has an important role in the repair of nerves and blood vessels, and anti-oxidative stress, etc. [2][3], it is widely used in clinical practice, especially effective in the treatment of cardiovascular diseases. Cardiovascular diseases, also known as circulatory diseases, are a group of heart and blood vessel diseases, usually closely related to atherosclerosis. With the continuous improvement of people's economic living standard and the rapid change of life style, cardiovascular disease has become one of the most serious chronic non-communicable diseases threatening people's health, and it is also the leading factor leading to the death of the disease.

KEYWORDS

Xuefu Zhuyu Decoction; cardiovascular disease; research progress

CITE THIS PAPER

Zhengfang Zhou, Panpan He, Peng Lei, Progress of Research on Clinical Application of Xuefu Zhuyu Decoction in Cardiovascular Diseases. MEDS Chinese Medicine (2024) Vol. 6: 57-62. DOI: http://dx.doi.org/10.23977/medcm.2024.060108.

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