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  4. Vol 5, Issue 2, 2024

Study on the Effects of Remimazolam on Heart Rate, Blood Pressure, and Respiratory Rate in Pain-free Gastrointestinal Endoscopy

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DOI: 10.23977/medsc.2024.050212 | Downloads: 8 | Views: 53

Author(s)

Jing Sui 1, Chunyong Tang 1

Affiliation(s)

1 Deyang People's Hospital, Deyang, Sichuan, 618000, China

Corresponding Author

Jing Sui

ABSTRACT

To investigate the effects of remimazolam on heart rate, blood pressure, and respiratory rate in patients underwent pain-free gastrointestinal endoscopy. A total of 120 patients undergoing pain-free gastrointestinal endoscopy were included in this study and randomly divided into experimental group and control group, with 60 cases in each group. The experimental group was given remimazolam for sedation, while the control group was given conventional sedatives. The heart rate, blood pressure, and respiratory rate of the patients were measured before the examination, during the examination, and at 15 and 30 minutes after the examination. The heart rate and blood pressure of the experimental group during the examination were significantly lower than those of the control group (P < 0.05); however, there was no significant difference in respiratory rate at each time point (P > 0.05). The sedation effect of the experimental group was significantly better than that of the control group (p = 0.006), but there was no significant difference in the scores at 15 and 30 minutes after the examination (p > 0.05). There was no significant difference in adverse reactions between the two groups (p > 0.05). Remimazolam can effectively reduce the heart rate and blood pressure of patients during pain-free gastrointestinal endoscopy, provide good sedation effect, and have minimal impact on respiratory rate, thus demonstrating good safety.

KEYWORDS

Remimazolam; pain-free gastrointestinal endoscopy; heart rate; blood pressure; respiratory rate

CITE THIS PAPER

Jing Sui, Chunyong Tang, Study on the Effects of Remimazolam on Heart Rate, Blood Pressure, and Respiratory Rate in Pain-free Gastrointestinal Endoscopy. MEDS Clinical Medicine (2024) Vol. 5: 78-83. DOI: http://dx.doi.org/10.23977/medsc.2024.050212.

REFERENCES

[1] Q. Mengna, "The Effect of Remimazolam on the Respiratory and Circulatory Systems of Patients Undergoing Painless Gastrointestinal Endoscopy Anesthesia," Medical Theory and Practice, 2022(035-009).
[2] L. Fugui, W. Yun, M. Yingcai, "The Application of Remimazolam Besylate in Painless Gastrointestinal Endoscopy in the Elderly and Its Impact on Hemodynamics," Shaanxi Medical Journal, 2022, 51(2):222-225.
[3] L. Huijun, Y. Zhao Ying, "The Effect of Fixed Low-Dose Remimazolam Combined with Etomidate in Painless Gastrointestinal Endoscopy in Elderly Patients with Hypertension," Lingnan Emergency Medicine Journal, 2023(6):571-573,579.
[4] H. Shijun, Y. Yan, "The Application of Remimazolam Besylate in Painless Gastrointestinal Endoscopy in the Elderly and Its Impact on Hemodynamics," Medical Diet Therapy and Health, 2022, 20(26):58-60.
[5] Z. Lili, L. Longhua, "A Clinical Study of Remimazolam Combined with Nalbuphine in Painless Gastrointestinal Endoscopy in Elderly Patients with Hypertension," Modern Medicine and Health Research (Electronic Edition), 2023(022):007.

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