Author(s)

Jiayue Yang

Corresponding Author

Jiayue Yang

ABSTRACT

ecDNA is a unique circular DNA located outside the cell chromosomes. By enriching the experimental data on the database and analyzing survival, we found that ecDNA acts on HNSC cancer species, which mainly has a huge impact on the immune system, and the survival time of the ecDNA-positive group will decline from a trend. At the same time, it was found that ecDNA may be a biological process that acts on biological proteins in ESCA cancer species.

KEYWORDS

ecDNA, HNSC, ESCA, Immune System, Big Data