Education, Science, Technology, Innovation and Life
Open Access
Sign In

Advancements in the Research Status of the Application of Polygonatum Sibiricum Granules

Download as PDF

DOI: 10.23977/afshn.2023.050106 | Downloads: 20 | Views: 379

Author(s)

Yuqing Shu 1, Jiahao Cheng 2, Bochao Yan 2, Lihan Zheng 2, Anqi Jiang 2, Haiyin Jiang 3

Affiliation(s)

1 School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, 311399, China
2 Hangzhou Medical College, Hangzhou, Zhejiang, 311300, China
3 College of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, 311300, China

Corresponding Author

Haiyin Jiang

ABSTRACT

Polygonatum sibiricum, a traditional Chinese medicine with food-medicine homology, contains various bioactive components beneficial to human health, such as polysaccharides, saponins, anthraquinones, alkaloids, cardenolides, lignans, vitamins, etc. Polygonatum sibiricum granules are a Chinese patent medicine prepared from the dried rhizomes of Polygonatum sibiricum. They exhibit extensive pharmacological activities, including nourishing Yin, benefiting the kidney, tranquilizing the mind, and modulating the immune system. In recent years, there has been growing attention to the research on Polygonatum sibiricum granules. Clinically, they have been used as an adjuvant therapy for various diseases involving the urinary, endocrine, cardiovascular, and digestive systems. Current research focuses on three main areas: pharmacological effects, drug-drug interactions, and clinical applications of Polygonatum sibiricum granules. This paper reviews the research progress on the compatibility of Polygonatum sibiricum granules and their clinical applications, aiming to provide references for researchers involved in the development of Polygonatum sibiricum granules.

KEYWORDS

Polygonatum Sibiricum; Pharmacological action; Clinical application; Drug-drug interactions; Granules

CITE THIS PAPER

Yuqing Shu, Jiahao Cheng, Bochao Yan, Lihan Zheng, Anqi Jiang, Haiyin Jiang, Advancements in the Research Status of the Application of Polygonatum Sibiricum Granules. Advances in Food Science and Human Nutrition (2023) Vol.5: 46-51. DOI: http://dx.doi.org/10.23977/afshn.2023.050106.

REFERENCES

[1] Xiaolan Wu, Guangxin Zhang, Yuqin Wang. Experimental Study on Antioxidant Effect of Polygonum polygonum polysaccharide on rats[J]. China Modern Doctor, 2011, 49(05): 6-11.
[2] Chunyan Zheng, Wang Haofen, Zhang Tingting. Study on the antibacterial and anti-inflammatory effects of Polygonum flavescens polysaccharide[J]. Journal of Anhui Normal University (Natural Science), 2010, 33(03): 272-275.
[3] Wei Su, Zhao Li, Liu Jiantao, et al. Study on Bacteriostasis and Anti-oxidation of Polyonatic Sibiricum Polysaccharides[J]. Food Science, 2007, (08): 55-57.
[4] Cheng Peng, Cao Xiaoyu, Ceng Qinghua. Establishment of keratoconjunctivitis model and study on the anti-inflammatory pharmacology of Polvgonum [J]. Traditional Chinese Drug Research and Clinical Pharmacology, 1996, (04): 49-51.
[5] Mingjun Yu, Wang Haiming. Research on miR-142-3p on inhibiting cell proliferation in thyroid cancer cells[J]. Health Research, 2021, 41(02): 164-167.
[6] Caiping Zhu. Study on Structure and Bioactivities of Lycium Barbarum Polysaccharide [D]. China Academic Journal Electronic Publishing House, 2006.
[7] Jiexin Wang, Ding Yan, Wang Qian, et al. Study on Chemical Constituents and Granule Preparation Technology of Lycium barbarum—Huangjing [J]. Chinese Journal of Ethnomedicine and Ethnopharmacy, 2020, 29(23): 24-31.
[8] Zhen Wu, He Fule. Formulation and efficacy evaluation ofRubi Fructus-Polygonatum granule health food[J]. Health Research, 2021, 41(02): 160-163.
[9] Ruiqin Cui, Ding Ying. Effects of cuscuzihuangjing Granules on ovarian injury and snad4mRNA expression in female rats with reproductive injury induced by tripterygium glycosides [J]. Lishizhen Medicine and Materia Medica Research, 2009, 20(12): 3149-3150.
[10] Yuanxue Wang. Study on Erjingfang polysaccharide extract quality standard and its effects on blood glucose and blood lipid in experimental type 2 diabetic mice[D]. China Academic Journal Electronic Publishing House, 2015.
[11] Jinghui Wang, Liu Xia. Application effect of Huaiqihuang granule in the treatment of nephrotic syndrome in children [J]. Clinical Research and Practice, 2022, 7(07): 137-140.
[12] Cuirong Duan, Li Zhihui, Zhang Yi, et al. Effect of Huaiqihuang Granules on hemorheology and serum hs-CRP in children with purpura nephritis[J]. Guiding Journal of Traditional Chinese Medicine and Pharmacy, 2017, 23(03): 94-95.
[13] Shulin Zhang, Cui Lanwei. Research Progress on Huai’er and Its Compound Preparation Huai-qi-huang Granule [J]. Medical Recapitulate, 2015, 21(01): 114-116.
[14] Wu Xuming, Yaping Xu. Effect of Huaiqihuang on OVA-induced apoptosis of eosinophil cells and immunoregulatory factors in asthmatic rats[J]. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine, 2020, 30(1): 14-18, 23.
[15] Deyu Zhao, Liu Hongxia, Tian Man, et al. Multicenter and random clinical study of Huaiqihuang granule combined with inhaled corticosteroids in the treatment of bronchial asthma in children [J]. Chinese Journal of Practical Pediatrics, 2020, 35(05): 355-358.
[16] Chong Xu. Effect of Huaiqihuang Granules assisted ICS treatment on pulmonary function and clinical symptoms in children with bronchial asthma[J]. journal of Mathematical Medicine, 2022, 35(06): 862-865.
[17] Taohong Xie, Feng Hui, Xie Peiyang. Effect of Huaiqihuang Granules combined with ceftazidime on inflammatory factors and immune function in children with mycoplasma pneumoniae pneumonia[J]. Drug Evaluation Research, 2019, 42(10): 2033-2036.
[18] Guiqin Du. Effect of Huaiqihuang granule on children with respiratory syncytial virus bronchiolitis and its immunomodulatory effect [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(06): 484-486.
[19] Yanling Li. Immunoregulation of Huaiqihuang Granule on children with respiratory tract virus bronchiolitis [J]. Drug Evaluation Research, 2016, 39(03): 417-420.
[20] Hongfeng Wang. Clinical observation on treatment for respiratory syncytial virus bronchiolitis with Huaiqihuang Granule [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2017, 9(02): 144-146.
[21] Yanyan Guo. Clinical Effects of Huaiqihuang Particle Combined with Montelukast Sodiumin Treated Children with Cough Variant Asthma[J]. Journal of Pediatric Pharmacy, 2014, 20(03): 25-28.
[22] Dan Chen, Guo Qing. Observation on the efficacy of Montelukast sodium and Huaiqihuang granules in preventing the recurrence of asthmatic bronchitis [J]. Chinese Journal of Modern Drug Application, 2015, 9(22): 140-141.
[23] Lin Liu, Wu Yi, Meng Lingjian, et al. Effects of Huaiqihuang Granule Combined with Inhaled Glucocorticoid on Pulmonary Function, Cellular Immune Factors and CCL3 and CCL5 Levels in Children with Bronchial Asthma[J]. Progress in Modern Biomedicine, 2022, 22(24): 4781-4785.
[24] Shuyuan Liu, Wang Shaojie, Gui Meiru, et al. Clinical observation of 30 cases of allergic purpura in children treated with Huaiqihuang granules[J]. Journal of Pediatrics of Traditional Chinese Medicine, 2019, 15(01): 55-58.
[25] Na An, Zhang Guying, Li Ruihong, et al. Meta-analysis on Effectiveness of Huaiqihuang Granules combined with Western Medicine in Treatment of Asthma in Children[J]. Guiding Journal of Traditional Chinese Medicine and Pharmacy, 2020, 26(12): 122-126.
[26] Na Hao, Liu Yang, Guo Luxuan, et al. Mechanism and clinical research progress of Huaiqihuang granule in chronic kidney disease [J]. Chinese Journal of Experimental Traditional Medical Formulae, 2022, 1-12.
[27] Min Hao, Zhao Ming, Li Yuanyuan, et al. A clinical study on treating the lung Qi-deficiency type of cough variant asthma in children with the Huaiqihuang granules[J]. Clinical Journal of Chinese Medicine, 2022, 14(29): 62-65.
[28] Donghong Chen, Han Zhigang, Si Jinping. Huangjing (Polygonati rhizoma) is an emerging crop with great potential to fight chronic and hidden hunger[J]. Science China Life Sciences, 2021, 64(9): 1564-1566. 

All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.