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A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of a Dietary Supplement (Viskin EX5®) in Improving Skin Condition of Healthy Asian Women

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DOI: 10.23977/afshn.2023.050110 | Downloads: 62 | Views: 778


Binbin Song 1, Jingjing Dai 1, Naizhuang Wang 1, Wai Fun Mok 1


1 Eternal Grace PTE. LTD, 128 Tuas South Avenue 3#01-05, JTC Space @ Tuas Biomedical Park, 637370, Singapore

Corresponding Author

Jingjing Dai


The skin undergoes noticeable changes as it ages, such as the loss of moisture, uneven darkening of skin tone, pigmentation, and the formation of wrinkles. While traditional topical skin care products are commonly used, specific dietary supplements offer the potential to improve skin conditions from within and provide a more comprehensive approach to skincare. A randomized double-blind clinical intervention was conducted to evaluate the effectiveness of Viskin EX5®, a nutritional supplement containing fruit extract and vitamins, in improving skin conditions. 32 healthy Asian women were randomly assigned to take either two tablets of Viskin EX5® (150 mg) or a placebo daily for eight weeks. Skin water content, skin color, and wrinkle area were measured at the beginning of the study and after four and eight weeks. Additionally, participants completed questionnaires at four and eight weeks to provide subjective feedback. Objective measurements of skin parameters revealed that Viskin EX5® significantly improved facial skin hydration compared to the placebo. The supplement also led to a significant reduction in skin melanin value, pigmentation density, and skin unevenness. Changes in skin colorimetric parameters, such as L* value, b* value, and ITA° degree, indicated a lighter skin tone. Furthermore, the areas of crow's feet and nasolabial folds were significantly reduced, with most skin indicators showing significant improvement at four weeks and further enhancement at eight weeks (p<0.05). Participants in the Viskin EX5® group generally reported that the supplement did not cause any bodily discomfort and resulted in improved skin condition.Viskin EX5®, consisting of fruit extract and vitamins, was found to be a safe and effective method for increasing skin moisture content, whitening skin, and reducing wrinkles. The results suggest that this nutritional supplement can provide comprehensive benefits for skin health.


Dietary supplement, Skin health, Skin aging, Fruit extract


Binbin Song, Jingjing Dai, Naizhuang Wang, Wai Fun Mok, A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of a Dietary Supplement (Viskin EX5®) in Improving Skin Condition of Healthy Asian Women. Advances in Food Science and Human Nutrition (2023) Vol.5: 77-84. DOI:


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