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mNGS: A novel method for the diagnosis of Chlamydia psittaci infection

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DOI: 10.23977/medbm.2024.020209 | Downloads: 3 | Views: 168

Author(s)

Lianlian Yu 1, Yuefeng Li 2, Jianhua Gong 3

Affiliation(s)

1 Department of Medicine, Yangtzeu University, Jingzhou, China
2 Department of Respiratory Medicine, Liaocheng Veterans Hospital, Liaocheng, China
3 Department of Respiratory and Critical Care, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China

Corresponding Author

Lianlian Yu

ABSTRACT

Psittacosis is a zoonotic disease caused by Chlamydia psittaci infection; human infections with Chlamydia psittaci usually originate from contact with infected animals, and studies have confirmed the existence of the human-to-human route of transmission, which also suggests that Chlamydia psittaci infections have a high risk of causing public health and safety incidents. Previous methods for detecting Chlamydia psittaci include polymerase chain reaction (different targets), serological assays (complement binding reaction, enzyme-linked immunosorbent assay, immunofluorescence assay, and immunoperoxidase assay), and isolation cultures, with the emergence of macrogene second-generation sequencing mNGS as a new diagnostic tool. Since the emergence of mNGS, there has been a significant increase in the number of studies on Chlamydia psittaci infections. In this paper, we will review the above case reports to help public health and medical practitioners to identify the disease earlier and provide timely and appropriate treatment, so as to reduce the risk to the public health and the pressure on the patients' medical care.

KEYWORDS

Chlamydia psittaciosis, mNGS, diagnosis

CITE THIS PAPER

Lianlian Yu, Yuefeng Li, Jianhua Gong, mNGS: A novel method for the diagnosis of Chlamydia psittaci infection. MEDS Basic Medicine (2024) Vol. 2: 49-56. DOI: http://dx.doi.org/10.23977/medbm.2024.020209.

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